Lower prevalence of pre-morbid neurological illness in African-Caribbean than White psychotic patients in England

McKenzie, Kwame; Jones, Peter B.; Lewis, Shôn; Williams, Marc; Toone, B.; Sham, Pak C.; Murray, Robin M.

doi:10.1017/s0033291702006190

Cited by 12 publications

(12 citation statements)

References 21 publications

(29 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The migration effect is not due to higher rates in the émigrés' country of origin. [9][10][11] This, along with the finding that lifetime morbidity risks for parents of black Caribbean and white subjects with schizophrenia are similar 42 and the lack of neurodevelopment markers in black Caribbean people who develop schizophrenia, 43 has been the main evidence against a predominantly genetic explanation of increased incidence.…”

Section: Meaning Of the Findingsmentioning

confidence: 99%

Raised Incidence Rates of All Psychoses Among Migrant Groups

Coid

Kirkbride²,

Barker³

et al. 2008

Arch Gen Psychiatry

193

View full text Add to dashboard Cite

Both first- and second-generation immigrants were at elevated risk for both nonaffective and affective psychoses, but this varied by ethnicity. Our results suggest that given the same age structure, the risk of psychoses in first and second generations of the same ethnicity will be roughly equal. We suggest that socioenvironmental factors operate differentially by ethnicity but not generation status, even if the exact specification of these stressors differs across generations. Research should focus on differential rates of psychoses by ethnicity rather than between generations.

show abstract

Section: Meaning Of the Findingsmentioning

confidence: 99%

Raised Incidence Rates of All Psychoses Among Migrant Groups

Coid

Kirkbride²,

Barker³

et al. 2008

Arch Gen Psychiatry

193

View full text Add to dashboard Cite

show abstract

“…More speculatively, it has been proposed that cephalopelvic disproportion arising from improved nutritional standards could lead to an elevated incidence of schizophrenia among second-generation migrants (64). Two studies have investigated history of obstetric complications in African Caribbean versus white British-born patients (65,66). Both studies found fewer obstetric complications in African Caribbean patients, and no differences in first-versus second-generation African Caribbean patients (65).…”

Section: How Well Do Current Hypotheses Concerning Migrants Fit the Dmentioning

confidence: 99%

Schizophrenia and Migration: A Meta-Analysis and Review

Cantor‐Graae¹,

Selten²

2005

AJP

1,051

726

View full text Add to dashboard Cite

show abstract

“…African Caribbeans are approximately 40% less likely to suffer from a continuous illness than British whites, 46 and it is suggested that they are less likely to have a history of obstetric complications or neurological illness premorbidly. 47 It has been hypothesized that the good symptomatic prognosis reflects increased rates of illness in less neurologically and genetically vulnerable people who have had relatively normal early development but have been exposed to social stressors that have promoted psychosis. One possible contributing factor is racial dis-crimination.…”

Section: Issues Concerning Ethnicitymentioning

confidence: 99%

Biological, Life Course, and Cross-Cultural Studies All point Toward the Value of Dimensional and Developmental Ratings in the Classification of Psychosis

Dutta¹,

Greene²,

Addington³

et al. 2007

Schizophrenia Bulletin

Self Cite

View full text Add to dashboard Cite

The diagnostic criteria for schizophrenia in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) are based on the premise that it is a discrete illness entity, in particular, distinct from the affective psychoses. This assumption has persisted for more than a century, even though patients with a diagnosis of schizophrenia show a wide diversity of symptoms and outcomes, and no biological or psychological feature has been found to be pathognomonic of the disorder. However, there has been sustained, and indeed growing, criticism of the concept. For example, writing about the diagnosis of schizophrenia more than a decade ago,2 one of Britain's most sophisticated nosological experts, Ian Brockington, enjoined "It is important to loosen the grip which the concept of 'schizophrenia' has on the minds of psychiatrists. Schizophrenia is an idea whose very essence is equivocal, a nosological category without natural boundaries, a barren hypothesis. Such a blurred concept is 'not a valid object of scientific enquiry'."3 Should Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition(DSM-V), persist with the neo-Kraepelinian concept of schizophrenia with all its defects, or should it deconstruct psychosis into its component dimensions? In this article, we will address the question by considering 2 main themes, firstly, the role of culture and ethnicity in the diagnosis of psychosis, and secondly, a life course approach to understanding psychosis. We will then discuss whether more progress would be achieved in DSM-V by abandoning the familiar categorical system and instead moving to a dimensional system which rates both developmental impairment and symptom factor scores. However, we will begin by briefly reviewing the recent history of the classification of the psychoses.

show abstract

Lower prevalence of pre-morbid neurological illness in African-Caribbean than White psychotic patients in England

Abstract: African-Caribbean patients with psychosis have experienced less pre-morbid neurological illness.

Cited by 12 publications

References 21 publications

Raised Incidence Rates of All Psychoses Among Migrant Groups

Raised Incidence Rates of All Psychoses Among Migrant Groups

Schizophrenia and Migration: A Meta-Analysis and Review

Biological, Life Course, and Cross-Cultural Studies All point Toward the Value of Dimensional and Developmental Ratings in the Classification of Psychosis

Contact Info

Product

Resources

About