Lower fluid and fruits / vegetable intake in questionable dementia among older Hong Kong Chinese

Lee, J.; Lam, Linda Chiu Wa; Woo, Jean; Kwok, Timothy

doi:10.1007/s12603-010-0008-y

Cited by 18 publications

(9 citation statements)

References 37 publications

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“…Of the 359 citations identified from database searches, nine articles met the inclusion criteria and were included in the meta-analysis, including five cohort studies ( Barberger-Gateau et al, 2007 ; Vercambre et al, 2009 ; Hughes et al, 2010 ; Ritchie et al, 2010 ; Chen et al, 2012 ) and four cross-sectional studies ( Lee et al, 2010 ; Roberts et al, 2010 ; Wu et al, 2011 ; Chan et al, 2013 ). The study selection process is shown in Figure 1 .…”

Section: Resultsmentioning

confidence: 99%

Increased Consumption of Fruit and Vegetables Is Related to a Reduced Risk of Cognitive Impairment and Dementia: Meta-Analysis

Jiang

Huang

Song

et al. 2017

Front. Aging Neurosci.

103

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Background: Increased consumption of fruit and vegetables has been shown to be associated with a reduced risk of cognitive impairment and dementia in many epidemiological studies. The purpose of this study was to assess the strength of this association in a meta-analysis.Methods: We identified relevant studies by searching Medline, Embase, and Cochrane Library electronic databases (from 1970 to January 2016). Study were included if they reported relative risks and corresponding 95% confidence intervals (CIs) of cognitive impairment and dementia with respect to frequency of fruit and vegetable intake.Results: Nine studies (five cohort studies and four cross-sectional studies) met the inclusion criteria and were included in the meta-analysis. There were a total of 31,104 participants and 4,583 incident cases of cognitive impairment and dementia. The meta-analysis showed that an increased consumption of fruit and vegetables was associated with a significant reduction in the risk of cognitive impairment and dementia (OR = 0.80, 95% CI 0.71–0.89). Subgroup analysis indicated this inverse association was only found among participants with mean age over 65 years and combined sexes. Dose–response meta-analysis showed that an increment of 100 g per day of fruit and vegetable consumption was related to an approximately 13% (OR = 0.87, 95% CI 0.77–0.99) reduction in cognitive impairment and dementia risk. There was no potential publication bias in the meta-analysis and the dose–response meta-analysis.Conclusion: The increased consumption of fruit and vegetables is associated with a reduced risk of cognitive impairment and dementia.

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Section: Resultsmentioning

confidence: 99%

Increased Consumption of Fruit and Vegetables Is Related to a Reduced Risk of Cognitive Impairment and Dementia: Meta-Analysis

Jiang

Huang

Song

et al. 2017

Front. Aging Neurosci.

103

View full text Add to dashboard Cite

show abstract

“…The relationship between greater intake of vegetables and fruits and fish and better cognitive status is suggestive but not completely consistent. Better cognitive function or slow cognitive decline was associated with consumption of fish and vegetables and fruits (Kang et al ., ; Morris et al ., ; Lee et al ., ; Roberts et al ., ; Vizuete et al ., ). However, a study of 13,388 women found no association between total fruit intake and cognitive function (Kang et al ., ).…”

Section: Discussionmentioning

confidence: 98%

Dietary patterns and cognitive decline in Taiwanese aged 65 years and older

Tsai

2014

Int J Geriat Psychiatry

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Dietary patterns correlate with cognitive function in Taiwanese aged 65 years and older and can predict the occurrence of subsequent cognitive decline. Western dietary pattern increases the risk of cognitive decline over 8 years. This study suggests that a diet that involves frequent consumption of meat/poultry and eggs and infrequent consumption of fish, beans/legumes, and vegetables and fruits may adversely affect cognitive function in older Taiwanese.

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“…Altogether, 39 subjects were excluded according the above exclusion criteria. Totally 298 T2D patients completed Mini-Mental State Examination (MMSE) [18] and a short memory questionnaire [19]. Sixty-three T2D patients with MCI were detected as cases.…”

Section: Methodsmentioning

confidence: 99%

Relationship between inflammatory markers and mild cognitive impairment in Chinese patients with type 2 diabetes: a case-control study

et al. 2019

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Background Several studies have indicated that inflammatory markers were associated with the risk of mild cognitive impairment (MCI) in type 2 diabetes (T2D). Serum folate was related to MCI as well as inflammation. However, no studies have investigated the association between inflammatory markers and MCI taking account of serum folate level in T2D patients. This study aimed to conduct a case-control study to evaluate the association between inflammatory markers and MCI taking account of serum folate level in Chinese patients with T2D. Methods This study consisted of 126 T2D patients (63 cases with MCI and 63 controls without MCI). Clinical parameters, serum folate, high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α) were measured. Spearman correlation analysis and logistic regression analysis were used to analyze the association between the inflammatory markers and the risk of MCI in T2D patients. Results There were higher serum hs-CRP, IL-6 and TNF-α in T2D cases with MCI compared with the controls. Serum folate was negatively correlated with hs-CRP, TNF-α, and IL-6 ( P < 0.05). In multivariate analysis, there were significant associations between serum IL-6 or hs-CRP and MCI after adjusting for the confounding variables, however, the association between hs-CRP and MCI disappeared after further adjusting for serum folate. Further subgroup analysis revealed that the significant association between hs-CRP and MCI only existed in the low folate subgroup (< 7.0 μg/L; OR = 3.34, 95% CI: 1.05–10.64), not in the high folate subgroup (≥7.0 μg/L; OR = 2.16, 95% CI: 0.68–6.88) after adjusting for the confounding variables. Conclusions Serum IL-6 and hs-CRP were associated with the risk of MCI in Chinese patients with T2D. Serum folate might modify the association between serum hs-CRP and MCI in T2D patients.

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Lower fluid and fruits / vegetable intake in questionable dementia among older Hong Kong Chinese

Abstract: Older people with questionable dementia have lower intakes of vegetables, fruits and fluid than those who were cognitively normal. This may pose additional health risks, and increase their chance of progressing into dementia.

Cited by 18 publications

References 37 publications

Increased Consumption of Fruit and Vegetables Is Related to a Reduced Risk of Cognitive Impairment and Dementia: Meta-Analysis

Increased Consumption of Fruit and Vegetables Is Related to a Reduced Risk of Cognitive Impairment and Dementia: Meta-Analysis

Dietary patterns and cognitive decline in Taiwanese aged 65 years and older

Relationship between inflammatory markers and mild cognitive impairment in Chinese patients with type 2 diabetes: a case-control study

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