Aging is associated with declines in physical and cognitive performance. While there is no doubt about beneficial effects of physical exercise on proxies of strength and balance, the overall evidence for positive effects of resistance and balance training on executive functions is rather inconsistent. Whether the simultaneous exercising of strength and balance, i.e., instability resistance training, promotes executive functions in older adults is unknown. In the present trial, we tested the effects of unstable vs. stable resistance training on executive functions. Sixty-eight healthy older adults aged 65-79 years were randomly assigned to either an instability free-weight resistance training or one of two stable machine-based resistance training programs. Each group exercised twice a week on non-consecutive days for 10 weeks. Four tests to evaluate specific domains of executive functions were administered prior and following training: working memory, processing speed, response inhibition and set-shifting. the instability resistance training group improved working memory, processing speed and response inhibition from pre to post-test. In contrast, we found no improvements in executive functions for both stable resistance training groups. Our results demonstrate that 10 weeks of instability resistance training suffice to improve executive functions in older adults. The decline of neuromuscular control, motor performance and cognition with aging and adverse health outcomes such as functional limitations and possible falls are major health care issues of the 21 st century 1-3. Impaired executive functioning, as part of cognition, has been associated with reduced physical functioning and impaired locomotion in particular 3. Therefore, improving executive functions and/or slowing age-related decline, is of great interest. While, based on a recent Cochrane review, the evidence for computerised cognitive training is somewhat inconclusive 4 , physical exercise interventions appear to be beneficial for executive functions based on single studies 5-11. However, the overall evidence for beneficial effects of physical exercise interventions on executive functions is rather inconsistent 12,13. Accordingly, we aimed to systematically investigate challenging and cognitively demanding vs. less demanding physical exercises 11-13. Consequently, the effects of resistance training modalities with different cognitive and physical demands on executive functions in older adults were tested in this study. The conflicting findings can mainly be explained by the abundance of different cognitive outcomes, tests and the variety of different study designs 6 making comparisons difficult. Furthermore, Diamond and Ling 12,13 argue that the reason why simple "mindless" exercise interventions like aerobic training (e.g., running on a treadmill) or pure balance training have little or no effect on executive functions is that they lack any cognitive challenge, attention or social component. Studies employing resistance training show that it may impr...