“…55 Despite the lower socio-economic status, illiteracy, low immunization rates, regional conflict and high-risk tribal populations, the prevalence of HBV is lower in India and the rest of South Asia as compared to South-East Asia. 56 Despite all the odds, this lower prevalence of HBV in South Asia may be due to the fact that unlike the vertical transmission of HBV in South-East Asia, the predominant mode of transmission is horizontally in South Asia. 57,58 Chronic HBV infection in India is acquired in childhood, presumably before 5 years of age, through horizontal transmission.…”