Lower-bandpass filter frequency in P3 experiments: A possible cause for divergent results in schizophrenia research

Ebmeier, Klaus P.; Potter, Douglas D.; Cochrane, R H B; Crawford, John R.; Salzen, Eric A.

doi:10.1016/0006-3223(90)90537-c

Cited by 16 publications

(4 citation statements)

References 10 publications

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“…Pitch disparity (Weisbrod et al, 1997), response (counting vs. pressing button press), task (Ford, Mathalon, White, & Pfefferbaum, 2000;Salisbury, Rutherford, Shenton, & McCarley, 2001), target stimulus probability (Duncan, Perlstein, & Morihisa, 1987), and trial type sequence order (Duncan-Johnson, Roth, & Kopell, 1984;Gonsalvez, Gordon, Anderson, Pettigrew, & Barry) have been found to affect P300 amplitude differences between patients with schizophrenia and unaffected controls. Recording amplifier filter settings can distort P300 schizophrenia evaluation (Ebmeier, Potter, Cochrane, Crawford, & Salzen, 1990;Glabus et al, 1994). In addition, the theoretical implications of smaller P300 amplitude in schizophrenic patients are often unspecified.…”

Section: Schizophrenia and P300mentioning

confidence: 99%

Meta‐analysis of P300 and schizophrenia: Patients, paradigms, and practical implications

2003

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The goal of the present meta-analysis was to identify factors that contribute to P300 event-related brain potential (ERP) differences in patients with schizophrenia compared to unaffected controls in an attempt to characterize the clinically relevant dimensions underlying P300 deficits in patients with schizophrenia. P300 effect size (d) was smaller in amplitude and longer in latency in schizophrenic patients compared to normal controls, with the strongest effects obtained from the auditory oddball. Paranoid subtype demonstrated larger P300 amplitude effect sizes than other disease subtypes, and P300 latency effect size decreased with disease duration. Psychopathology severity and antipsychotic medications were unrelated to P300 amplitude effect size. Gender proportion, educational level, and stimulus and task variables also affected P300 amplitude and latency effect sizes. The findings are used to formulate a theoretical account of the empirical data and provide suggestions for maximizing the utility of the P300 component in the assessment of schizophrenia.

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Section: Schizophrenia and P300mentioning

confidence: 99%

Meta‐analysis of P300 and schizophrenia: Patients, paradigms, and practical implications

2003

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“…Some authors report that auditory ERPs contain a slow-wave element, and an inaccurate high-pass filter would cause ambiguous findings [12]. The filter setting may affect measures on amplitude and latency as well as those of coherence.…”

Section: Discussion S Effects Of Rtms On Erpsmentioning

confidence: 99%

“…The reasons that we selected these conditions were the following. First, the domain rhythm of EEG activity of normal subjects lies in the alpha band (8)(9)(10)(11)(12)(13). We considered that rTMS at 10 Hz has more effect on cortical activities than rTMS at a frequency lower or higher than the alpha range because responses of a dynamic system are stronger if the frequency of external effect is close or equal to its internal frequency.…”

Section: Methods and Materials S Subjectsmentioning

confidence: 99%

Comparisons of event-related potentials after repetitive transcranial magnetic stimulation

Jing¹,

Takigawa²,

Okamura³

et al. 2001

Journal of Neurology

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Effects of repetitive transcranial magnetic stimulation (rTMS) on the human cognitive process were investigated by examining auditory event-related potentials (ERPs) in 15 healthy subjects. Two rTMS trains were delivered over the left frontal area, with 30 pulses in each train. ERPs were recorded at 14 electrode sites on the scalp using a typical oddball protocol before and after rTMS. Tone stimuli (20% target and 80% standard) were delivered through earphones. Latency and amplitude of N100, P200, N200 and P300 were measured and compared during the study. To observe information flow between two electrode sites, directed coherence (DCOH) was calculated on the ERPs. Our results show that the effect of rTMS differs in the various ERPs components (P < 0.001). The latency of P300 significantly increased after stimulation, and the increase was more obvious in the frontal (18.6 ms) and central (15.8 ms) areas. The latency of P200 decreased in all areas. The amplitude of component N100 in the frontal and central areas decreased after rTMS. DCOH from the central area to the temporal area and DCOH from the parietal area to the temporal area were significantly higher than the DCOH between other areas (P < 0.01), and these properties were not affected by rTMS (P > 0.05). Information flow was driven from the frontal area to the parietal area after stimulation. Our results suggest that rTMS can suppress cognitive activities, showing an inhibitory effect on neurophysiological processes in the human brain. Since the temporal area is located at the terminus of the propagation pathways, it plays important roles in processing information in cognitive activities.

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“…Reduction in the P300 amplitude in the auditory odd-ball paradigm has been widely reported [3][4][5], but latency changes have not been so consistent. Some authors report increased P300 latencies in the auditory odd-ball para digm [4][5][6], whereas others have not observed the in creased P300 latency in schizophrenics [7,8]. Prolonga tion of P300 latency has been reported to be independent of both medication and the patient's clinical state [4].…”

Section: Introductionmentioning

confidence: 99%

Smaller Auditory P300 Amplitude in Schizophrenics in Remission

et al. 1995

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The P300 event-related potential (ERP) was recorded using the auditory oddball paradigm in 12 (6 male) schizophrenic (DSM-IIIR) patients in rigorously defined clinical remission. The ERP was also recorded in 10 (5 male) age-, sex-and education-matched control subjects. ERP latencies and amplitude were measured at Cz and Pz recording sites. Mean latencies of the P300 in schizophrenic patients in remission at Cz [343.6 ±31 (SD) ms] and Pz (346.15 ± 30 ms) did not differ from those of normals (Cz: 332.8 ± 23 ms, Pz: 323 ± 38 ms). The P300 ERP amplitude was significantly (p < 0.05) smaller in schizophrenics in remission at both Cz (9.2 ± 4.4 µV) and Pz (8.8 ± 4.4 µV) than in normals (Cz: 13.3 ± 2.90 µV; Pz: 12.71 ± 4.18 µV). The significance of the smaller auditory P300 amplitude in schizophrenia is discussed.

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Lower-bandpass filter frequency in P3 experiments: A possible cause for divergent results in schizophrenia research

Cited by 16 publications

References 10 publications

Meta‐analysis of P300 and schizophrenia: Patients, paradigms, and practical implications

Meta‐analysis of P300 and schizophrenia: Patients, paradigms, and practical implications

Comparisons of event-related potentials after repetitive transcranial magnetic stimulation

Smaller Auditory P300 Amplitude in Schizophrenics in Remission

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