Low vitamin D levels do not predict risk of autoimmune disease following alemtuzumab treatment for multiple sclerosis

Arnett, Simon; Sanchez, Sofia Jimenez; Downing, Jennifer; Boggild, Mike; Sun, Jing; Broadley, Simon

doi:10.1016/j.msard.2022.103511

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2022

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“…In one prospective study, investigators failed to observe an association between vitamin D insufficiency and alemtuzumab-induced autoimmunity. 9 The authors found that the female sex was the only associated risk factor with alemtuzumab-induced autoimmunity in their cohort. 9 Apart from anecdotes, no other studies to our knowledge specifically examined this potential association.…”

Section: Dear Editormentioning

confidence: 91%

“… 9 The authors found that the female sex was the only associated risk factor with alemtuzumab-induced autoimmunity in their cohort. 9 Apart from anecdotes, no other studies to our knowledge specifically examined this potential association. While there are no clinical studies that proved the role of vitamin D supplementation in preventing secondary autoimmunity in alemtuzumab-treated MS patients, we agree with Goischke that vitamin D supplementation is generally safe and accessible to patients.…”

Section: Dear Editormentioning

confidence: 91%

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