Low-toxic multi-liposomal containers for encapsulation of bioactive compounds

Novoskoltseva, Оlga А.; Ryabaya, Oxana; Позднякова, Н. В.; Yaroslavov, Alexander A.

doi:10.1016/j.colsurfa.2020.125282

Cited by 3 publications

(2 citation statements)

References 40 publications

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“…In other words, all the cationic QHECE groups participated in the electrostatic bonding to ALG. As shown earlier, the maximum turbidity, or the maximum size of particles, in the polyanion-polycation binary system is observed at an equimolar charge-to-charge ratio of both polymer components [29,41]. It follows from there that the maximum turbidity is reached when the concentration of the complexed anionic (ionized) ALG groups is equal to the concentration of the cationic QHECE groups: 1).…”

Section: Formation and Properties Of Alg-qhece Polycomplexesmentioning

confidence: 78%

Biodegradable Interpolycomplexes for Anti-Erosion Stabilization of Soil and Sand

et al. 2022

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A linear anionic polysaccharide, sodium alginate, electrostatically interacts with a cationic polysaccharide, quaternized hydroxyethyl cellulose ethoxylate, in aqueous solution, thus giving an interpolyelectrolyte complex. Aqueous solutions of the initial polysaccharides and polycomplexes with an excess of the cationic or anionic polymers were used for the stabilization of soil and sand against water erosion. Physicochemical, mechanical and biological properties of the polymers and coatings were characterized by gravimetric analysis, viscosimetry, mechanical strength assessment, cell viability, and cell-mediated degradation with the following main conclusions. (a) Non-stoichiometric polycomplexes with an excess of cationic or anionic units (“cationic” and “anionic” polycomplexes, respectively) form transparent solutions or stable-in-time dispersions. (b) The complexation results in a decrease in the viscosity of polymer solutions. (c) A complete dissociation of polycomplexes to the initial components is achieved in a 0.2 M NaCl solution. (d) Soil/sand treatment with 1 wt% aqueous solutions of polymers or polycomplexes and further drying lead to the formation of strong composite coatings from polymer(s) and soil/sand particles. (e) Cationic polycomplexes form stronger coatings in comparison with anionic polycomplexes. (f) The polymer–soil coatings are stable towards re-watering, while the polymer–sand coatings show a much lower resistance to water. (g) The individual polysaccharides demonstrate a negligible toxicity to Gram-negative and Gram-positive bacteria and yeast. (h) The addition of Bacillus subtilis culture initiates the degradation of the polysaccharides and polycomplexes. (i) Films from polysaccharides and polycomplexes decompose down to small fragments after being in soil for 6 weeks. The results of the work are of importance for constructing water-resistant, low toxicity and biodegradable protective coatings for soil and sand.

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Section: Formation and Properties Of Alg-qhece Polycomplexesmentioning

confidence: 78%

Biodegradable Interpolycomplexes for Anti-Erosion Stabilization of Soil and Sand

et al. 2022

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“…Liposomes are spherical shaped bilayers used to deliver and encapsulate lipophilic, hydrophilic, and amphiphilic bioactive substances in the food and pharmaceutical industries (Alexander et al, 2012; Novoskoltseva et al, 2020; Tai et al, 2018). Liposomes consist of an aqueous core and one or more bilayers composed of lipids such as cholesterol (which helps to stabilize bilayers) or phospholipids (which are suitable for protection and control release of the phytosterols at their target site of the liposomes).…”

Section: Different Encapsulation Techniques For Incorporation Of Phyt...mentioning

confidence: 99%

Novel encapsulation approaches for phytosterols and their importance in food products: A review

Pavani

Singha

Dash

et al. 2022

J Food Process Engineering

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Phytosterols are naturally occurring plant cell membranes, which have received greater attention in food industries due to their potential health benefits especially lowering low‐density lipoprotein (LDL) cholesterol levels within the human body. However, the application of phytosterols in various foods (aqueous‐based) is challenging due to their low water solubility and poor stability resulting in poor bioavailability/bioaccessibility. The encapsulation technique is considered as an alternative approach to protect phytosterols from various factors, thus improving their bioavailability and stability. This review aims in presenting a detailed study on techniques and technologies currently employed to encapsulate phytosterols. Based on recent studies, mostly used techniques are spray drying, freeze drying, spray chilling, emulsification, liposome entrapment, extrusion, electro‐spinning, and electro‐spraying. Various processing factors affecting phytosterol stability in fortified food have been outlined as well. Practical Applications Phytosterols are plant‐based bioactive compounds that have been commonly linked to having anti‐diabetic, anti‐inflammatory properties and cholesterol‐lowering effects. Consumption of processed and ready‐to‐eat foods lowers the intake of plant sterols in the human diet. Additionally, their availability in plant‐based foods is also limited. Phytosterol fortified foods are now available to fulfill the phytosterol requirement in our diet. The consumption of phytosterol enriched foods or supplements can be an alternative option to lower cholesterol levels in the human body. However, phytosterols are insoluble in water which results in poor bioavailability and stability. Furthermore, the incorporation of phytosterols in food products is difficult due to the probability of oxidation at higher processing temperatures and storage. Hence, encapsulation is an alternative approach to enhance phytosterols' stability and bioavailability.

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Hybrid polycomplexes of anionic alginate with a synthetic cationic polymer: attractive and poisonous for microorganisms

Sinelnikova,

Novoskoltseva,

Loiko

et al. 2024

Mendeleev Communications

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Low-toxic multi-liposomal containers for encapsulation of bioactive compounds

Cited by 3 publications

References 40 publications

Biodegradable Interpolycomplexes for Anti-Erosion Stabilization of Soil and Sand

Biodegradable Interpolycomplexes for Anti-Erosion Stabilization of Soil and Sand

Novel encapsulation approaches for phytosterols and their importance in food products: A review

Hybrid polycomplexes of anionic alginate with a synthetic cationic polymer: attractive and poisonous for microorganisms

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