Low to moderate dose 137 Cs (γ) radiation enhances M2 type macrophages function at short term associated with reduced inflammation at long term exposure in ApoE (-/-) mice
N. Rey,
T. Ebrahimian,
C . Gloaguen
et al.
Abstract:Effects of low doses of ionizing radiation on atherosclerosis are still a source of many uncertainties, and in particular whether these effects generate anti or pro-inflammatory responses. Furthermore, the delay of occurrence of such effects upon irradiation are unknown. Atheroprone ApoE(−/−) mice were exposed to single doses of 0, 0.05, 0.5 and 1 Gy of 137Cs (γ) at 10.35 mGy.min− 1 dose rate. Short term (24 hours) effects on bone marrow-derived macrophage polarization and long term (100 days) consequences on … Show more
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