Two-loop effects on the right-handed neutrino masses can have an impact on the low-energy phenomenology, especially when the right-handed neutrino mass spectrum is very hierarchical at the cut-off scale. In this case, the physical masses of the lighter right-handed neutrinos can be dominated by quantum effects induced by the heavier ones. Further, if the heaviest right-handed neutrino mass is at around the Planck scale, two-loop effects on the right-handed neutrino masses generate, through the seesaw mechanism, an active neutrino mass which is in the ballpark of the experimental values. In this paper we investigate extensions of the Planckscale lepton number breaking scenario by additional Higgs doublets (inert or not). We find that under reasonable assumptions these models lead simultaneously to an overall neutrino mass scale and to a neutrino mass hierarchy in qualitative agreement with observations.