Abstract:Immunization of health care personnel (HCP) is critically important to reduce healthcare-associated influenza infections substantially. During 2009During -2010 of all HCP at Kitano Hospital, Osaka, Japan, including 94% of pediatricians, received the monovalent unadjuvanted influenza A (H1N1) pdm09 vaccine.We evaluated the vaccine's immunogenicity. Sixteen pediatricians received 15 mg hemagglutinin antigen subcutaneously. Antibody titer assays were conducted using hemagglutination-inhibition antibody assay on … Show more
This review discusses factors and strategies that must be considered and addressed during immunogenicity assessments of pandemic influenza vaccines, which may provide useful information for future influenza pandemics.
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