Low rates of X‐Y recombination, not turnovers, account for homomorphic sex chromosomes in several diploid species of Palearctic green toads (Bufo viridis subgroup)

Stöck, Matthias; Savary, Romain; Betto‐Colliard, Caroline; Biollay, Sébastien; Jourdan-Pineau, Hélène; Perrin, Nicolas

doi:10.1111/jeb.12086

Cited by 61 publications

(77 citation statements)

References 44 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Most frogs with known systems of sex determination are male heterogametic. In Hyla, Bufo and Rana, recombination is reduced in males (Berset-Brändli et al, 2008;Stöck et al, 2013;Rodrigues et al, 2013), consistent with the Haldane-Huxley rule. However, we still do not know whether one of these patterns is the cause of the other.…”

Section: Discussionsupporting

confidence: 62%

High-density sex-specific linkage maps of a European tree frog (Hyla arborea) identify the sex chromosome without information on offspring sex

2015

View full text Add to dashboard Cite

Identifying homology between sex chromosomes of different species is essential to understanding the evolution of sex determination. Here, we show that the identity of a homomorphic sex chromosome pair can be established using a linkage map, without information on offspring sex. By comparing sex-specific maps of the European tree frog Hyla arborea, we find that the sex chromosome (linkage group 1) shows a threefold difference in marker number between the male and female maps. In contrast, the number of markers on each autosome is similar between the two maps. We also find strongly conserved synteny between H. arborea and Xenopus tropicalis across 200 million years of evolution, suggesting that the rate of chromosomal rearrangement in anurans is low. Finally, we show that recombination in males is greatly reduced at the centers of large chromosomes, consistent with previous cytogenetic findings. Our research shows the importance of high-density linkage maps for studies of recombination, chromosomal rearrangement and the genetic architecture of ecologically or economically important traits.

show abstract

Section: Discussionsupporting

confidence: 62%

High-density sex-specific linkage maps of a European tree frog (Hyla arborea) identify the sex chromosome without information on offspring sex

2015

View full text Add to dashboard Cite

show abstract

“…Empirical support for turnovers has been gathered from several fish [e.g. Tanaka et al, 2007;Cnaani et al, 2008;Ross et al, 2009] and amphibian systems, including Ranidae [Hotz et al, 1997;Miura, 2007] and Bufonidae [Malone and Fontenot, 2008;Stöck et al, 2011aStöck et al, , 2013.…”

mentioning

confidence: 99%

Maintenance of Ancestral Sex Chromosomes in Palearctic Tree Frogs: Direct Evidence from Hyla orientalis

Stöck

Savary²,

Zaborowska³

et al. 2013

Sex Dev

Self Cite

View full text Add to dashboard Cite

Contrasting with the situation found in birds and mammals, sex chromosomes are generally homomorphic in poikilothermic vertebrates. This homomorphy was recently shown to result from occasional X-Y recombinations (not from turnovers) in several European species of tree frogs (Hyla arborea, H. intermedia and H. molleri). Because of recombination, however, alleles at sex-linked loci were rarely diagnostic at the population level; support for sex linkage had to rely on multilocus associations, combined with occasional sex differences in allelic frequencies. Here, we use direct evidence, obtained from anatomical and histological analyses of offspring with known pedigrees, to show that the Eastern tree frog (H. orientalis) shares the same pair of sex chromosomes, with identical patterns of male heterogamety and complete absence of X-Y recombination in males. Conservation of an ancestral pair of sex chromosomes, regularly rejuvenated via occasional X-Y recombination, seems thus a widespread pattern among Hyla species. Sibship analyses also identified discrepancies between genotypic and phenotypic sex among offspring, associated with abnormal gonadal development, suggesting a role for sexually antagonistic genes on the sex chromosomes.

show abstract

“…Our estimate of an equal number of Y chromosome gains in Adephaga is more interesting. While some sex chromosomes are famous for avoiding decay and remaining homomorphic [e.g., ratite birds (Adolfsson and Ellegren 2013;) and anurans (Stock et al 2011;Stock et al 2013)], the situation in Adephaga is different. In this group, new Y chromosomes are evolving at the same rate they are lost.…”

Section: Discussionmentioning

confidence: 99%

Estimating Tempo and Mode of Y Chromosome Turnover: Explaining Y Chromosome Loss With the Fragile Y Hypothesis

Blackmon

Demuth

2014

Genetics

View full text Add to dashboard Cite

Chromosomal sex determination is phylogenetically widespread, having arisen independently in many lineages. Decades of theoretical work provide predictions about sex chromosome differentiation that are well supported by observations in both XY and ZW systems. However, the phylogenetic scope of previous work gives us a limited understanding of the pace of sex chromosome gain and loss and why Y or W chromosomes are more often lost in some lineages than others, creating XO or ZO systems. To gain phylogenetic breadth we therefore assembled a database of 4724 beetle species' karyotypes and found substantial variation in sex chromosome systems. We used the data to estimate rates of Y chromosome gain and loss across a phylogeny of 1126 taxa estimated from seven genes. Contrary to our initial expectations, we find that highly degenerated Y chromosomes of many members of the suborder Polyphaga are rarely lost, and that cases of Y chromosome loss are strongly associated with chiasmatic segregation during male meiosis. We propose the "fragile Y" hypothesis, that recurrent selection to reduce recombination between the X and Y chromosome leads to the evolution of a small pseudoautosomal region (PAR), which, in taxa that require XY chiasmata for proper segregation during meiosis, increases the probability of aneuploid gamete production, with Y chromosome loss. This hypothesis predicts that taxa that evolve achiasmatic segregation during male meiosis will rarely lose the Y chromosome. We discuss data from mammals, which are consistent with our prediction.

show abstract

Low rates of X‐Y recombination, not turnovers, account for homomorphic sex chromosomes in several diploid species of Palearctic green toads (Bufo viridis subgroup)

Cited by 61 publications

References 44 publications

High-density sex-specific linkage maps of a European tree frog (Hyla arborea) identify the sex chromosome without information on offspring sex

High-density sex-specific linkage maps of a European tree frog (Hyla arborea) identify the sex chromosome without information on offspring sex

Maintenance of Ancestral Sex Chromosomes in Palearctic Tree Frogs: Direct Evidence from <b><i>Hyla orientalis</i></b>

Estimating Tempo and Mode of Y Chromosome Turnover: Explaining Y Chromosome Loss With the Fragile Y Hypothesis

Contact Info

Product

Resources

About