LOW PREVALENCE OF METHICILLIN‐RESISTANT <i>STAPHYLOCOCCUS AUREUS</i> IN DUTCH NURSING HOMES

Greenland, Katie; Rijnders, Marlies; Mulders, Mick N.; Haenen, Anja; Spalburg, Emile; Kassteele, Jan van de; Neeling, Albert J. de; Stobberingh, Ellen E.

doi:10.1111/j.1532-5415.2011.03325.x

Cited by 26 publications

(17 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The MRSA prevalence we observed was lower than in MRSA surveys in recent years in the US [41][42][43][44][45], China [46], the UK [16], France [20], Ireland [15], and Italy [24], but higher than in the Netherlands and Sweden [14,22] (Table 3). …”

Section: Discussioncontrasting

confidence: 66%

“…MDRO are regarded as a potentially serious threat to elderly people living in long-term care facilities (LTCFs). Although various studies on the prevalence of MRSA in LTCFs in Germany [7][8][9][10][11][12][13] and other European countries [14][15][16][17][18][19][20][21][22][23][24][25] have been published (< 1% in the Netherlands and Sweden, > 20% in Ireland and the United Kingdom (UK)), studies on the prevalence of MRGN such as extended-spectrum betalactamase (ESBL)-producing Enterobacteriaceae and vancomycin-resistant enterococci (VRE) among nursing home residents in German and in European LTCFs are scarce [7,14,24,26,27]. Although an increasing trend in the occurrence of ESBL-producing Enterobacteriaceae and even CRO is found in hospitals all over Europe [1,3,28,29], a lack of knowledge on multidrug-resistant organisms (MDRO) in nursing homes has to be stated.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Current prevalence of multidrug-resistant organisms in long-term care facilities in the Rhine-Main district, Germany, 2013

Hogardt

Proba

Mischler³

et al. 2015

Eurosurveillance

View full text Add to dashboard Cite

Multidrug-resistant organisms (MDRO) and in particular multidrug-resistant Gram-negative organisms (MRGN) are an increasing problem in hospital care. However, data on the current prevalence of MDRO in long-term care facilities (LTCFs) are rare. To assess carriage rates of MDRO in LTCF residents in the German Rhine-Main region, we performed a point prevalence survey in 2013. Swabs from nose, throat and perineum were analysed for meticillin-resistant Staphylococcus aureus (MRSA), perianal swabs were analysed for extended-spectrum beta-lactamase (ESBL)-producing organisms, MRGN and vancomycin-resistant enterococci (VRE). In 26 LTCFs, 690 residents were enrolled for analysis of MRSA colonisation and 455 for analysis of rectal carriage of ESBL/MRGN and VRE. Prevalences for MRSA, ESBL/MRGN and VRE were 6.5%, 17.8%, and 0.4%, respectively. MRSA carriage was significantly associated with MRSA history, the presence of urinary catheters, percutaneous endoscopic gastrostomy tubes and previous antibiotic therapy, whereas ESBL/ MRGN carriage was exclusively associated with urinary catheters. In conclusion, this study revealed no increase in MRSA prevalence in LTCFs since 2007. In contrast, the rate of ESBL/MRGN carriage in German LTCFs was remarkably high. In nearly all positive residents, MDRO carriage had not been known before, indicating a lack of screening efforts and/or a lack of information on hospital discharge.

show abstract

Section: Discussioncontrasting

confidence: 66%

Section: Introductionmentioning

confidence: 99%

Current prevalence of multidrug-resistant organisms in long-term care facilities in the Rhine-Main district, Germany, 2013

Hogardt

Proba

Mischler³

et al. 2015

Eurosurveillance

View full text Add to dashboard Cite

show abstract

“…The MRSA prevalence is of the same order of magnitude as those described in previous studies. 11,19 These results indicate a consistently low MRSA prevalence over the last decade. Similar results were found in Germany, where no increase in MRSA was Isolate prevalence of ESBL-producing E. coli showed a large variation between LTCFs: from 1% to 33%.…”

Section: Discussionmentioning

confidence: 65%

“…8 -10 These studies suggest a high local prevalence of antimicrobial-resistant Escherichia coli, including those producing an ESBL. Studies performed in 2009 covering a larger part of the Netherlands found low prevalence of 0.3% 11 and 2% 12 of MRSA in Dutch LTCFs.…”

Section: Introductionmentioning

confidence: 99%

Carriage of antimicrobial-resistant commensal bacteria in Dutch long-term-care facilities

Verhoef

Roukens

Greeff

et al. 2016

J. Antimicrob. Chemother.

Self Cite

View full text Add to dashboard Cite

Objectives: The objective of this study was to assess carriage of antimicrobial-resistant commensal microorganisms, i.e. Escherichia coli and Staphylococcus aureus, and its predictors in long-term-care facilities (LTCFs).Methods: Nasal swabs and/or urine or incontinence samples were collected from participating residents in 111 LTCFs and tested for the presence of S. aureus and/or E. coli, respectively. Antimicrobial resistance to eight antimicrobials was linked to antimicrobial usage in the year preceding sampling and to LTCF characteristics. Using multilevel logistic regression, predictors of carriage of ESBL-producing E. coli in LTCFs were identified.Results: S. aureus was identified in 1269/4763 (26.6%) nasal swabs, including 13/4763 (0.3%) MRSA carriers in 9/107 (8%) LTCFs. Of the 5359 urine/incontinence samples, 2934 (55%) yielded E. coli, including 123 (4.2%) producing ESBL, which were found in 53/107 locations (range 1% -33%). For all but one antimicrobial (i.e. nitrofurantoin) .20% of isolated E. coli were resistant. Multilevel multivariable logistic regression identified two predictors of carriage of ESBL-producing E. coli: (i) antimicrobial usage (OR 1.8, 95% CI 1.1 -3.0 for each extra 50 DDD/1000 residents/day); and (ii) presence of MRSA carriers in the LTCFs (OR 2.4, 95% CI 1.0-5.6). Conclusions:The low proportion of 4.2% ESBL-producing E. coli and the low prevalence of 0.3% MRSA carriage found in LTCF residents suggest that Dutch LTCFs are not yet an important reservoir of MDR potential pathogens. Nevertheless, the large variation between LTCFs warrants close monitoring of antimicrobial resistance in LTCFs.

show abstract

“…Genetische Analysen zeigen, dass es sich dabei in der Regel um Stämme handelt, die auch in Krankenhäusern prävalent sind [41]. Internationale Daten geben Präva-lenzen von 0,33% in den Niederlanden bis hin zu 52% in den USA an [42,43]. Auch für VRE bei Altenheimbewohnern sind international Prävalenzen zwischen ca.…”

Section: Bedeutung Antibiotikaresistenter Bakterien Bei Alten Menscheunclassified

Herausforderungen durch Infektionen und mehrfach-resistente Bakterien bei alten Menschen in Heimen

Ruscher

Schaumann

Mielke

2012

Bundesgesundheitsbl.

View full text Add to dashboard Cite

LOW PREVALENCE OF METHICILLIN‐RESISTANT STAPHYLOCOCCUS AUREUS IN DUTCH NURSING HOMES

Cited by 26 publications

References 6 publications

Current prevalence of multidrug-resistant organisms in long-term care facilities in the Rhine-Main district, Germany, 2013

Current prevalence of multidrug-resistant organisms in long-term care facilities in the Rhine-Main district, Germany, 2013

Carriage of antimicrobial-resistant commensal bacteria in Dutch long-term-care facilities

Herausforderungen durch Infektionen und mehrfach-resistente Bakterien bei alten Menschen in Heimen

Contact Info

Product

Resources

About