Low prevalence of hepatitis C virus infection in Amerindians from Western Venezuela

Monsalve-Castillo, Francisca; Chacín-Bonilla, Leonor; Atencio, Ricardo; Espinoza, Leticia Porto; Costa-León, Luciana; Echevarría, José Manuel

doi:10.1590/s0074-02762007000100018

Cited by 8 publications

(6 citation statements)

References 16 publications

(14 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The overall seroprevalence of HBsAg and anti-HBc was in agreement with other studies carried out among Latin American Amerindians where low HBsAg and a higher anti-HBc seroprevalence were reported. [24][25][26] The variation of HBV prevalence in these populations may be due to cultural habits within each community and to the extent of geographic and social isolation, since no HIV-1, HTLV-1/2, and HCV infections were observed among them 24,25 (M. Biglione, personal communication).…”

Section: Discussionmentioning

confidence: 99%

New natural variants of hepatitis B virus among Amerindians from Argentina with mainly occult infections

Delfino

Berini

Eirin

et al. 2012

Journal of Clinical Virology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

New natural variants of hepatitis B virus among Amerindians from Argentina with mainly occult infections

Delfino

Berini

Eirin

et al. 2012

Journal of Clinical Virology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

“…More than 15 years ago, the prevalence of HCV infection among hemodialysis patients in Venezuela was between 25% and 71% 3,12 . However, in recent years, HCV infection in hemodialysis patients has not been observed and its prevalence in other populations is no higher than 1%, suggesting the low prevalence of anti-HCV in the country [8][9][10] .The aim of this study was to establish the incidence of HCV in a longitudinal study of patients undergoing hemodialysis in one unit of the University Hospital, Maracaibo, Zulia State, Venezuela. Over a two year period, [2007][2008][2009] 29 patients aged between 15 and 75 years (mean ± DS: 45 ± 39.5 years), who began dialysis treatment at the Maracaibo University Hospital were monitored.…”

mentioning

confidence: 99%

Hepatitis C virus infection in hemodialysis patients in Maracaibo, Venezuela

Monsalve-Castillo

Gómez-Gamboa

Chacín-Bonilla

et al. 2012

Rev. Inst. Med. trop. S. Paulo

Self Cite

View full text Add to dashboard Cite

Over a two year period, the incidence of hepatitis C virus (HCV) infection was evaluated in 29 hemodialysis patients, aged between 15 and 75 years (mean ± SD: 45 ± 39.5 years), from the University Hospital Hemodyalisis Unit, Maracaibo, Zulia State, Venezuela. Anti-HCV antibodies were determined using a fourth generation ELISA (Innotest HCV Ab IV) kit and positive blood samples were tested using a recombinant assay kit (Inno-LIA HCV Ab III), both kits from Innogenetics N.V., Belgium. The findings indicate a lack of HCV seroconversion in the hemodialysis patients over the study period, confirmed by the recombinant assay. Risk factors for HCV infection were 0.3270 (95% confidence interval: 0.01323-8.080) in patients undergoing hemodialysis. The findings suggest a lack of significant sources for HCV infection due to the preventive measures to avoid its transmission in the hemodialysis unit.

show abstract

“…Sin embargo, con base en estudios previos en la región (33,41), si existe subestimación, ésta debería ser mínima. A pesar de esta limitación, el presente estudio tiene algunas fortalezas: los participantes fueron escogidos al azar, la participación de los individuos seleccionados fue alta y la muestra estudiada fue representativa.…”

Section: Discussionunclassified

Baja prevalencia de la infección por el virus de la hepatitis C en una población de reclusos, Maracaibo, Venezuela

et al. 2009

View full text Add to dashboard Cite

Introducción. Las conductas de alto riesgo presentes en los centros de reclusión incrementan la probabilidad de transmisión de la infección por el virus de la hepatitis C. En Venezuela no se han realizado estudios del virus en estos centros, por lo que se desconoce la relevancia de la infección en ellos. Objetivo. Estimar la prevalencia del virus de la hepatitis C y los posibles factores de riesgos involucrados en la transmisión del virus en reclusos de la cárcel de Sabaneta, Maracaibo, Venezuela. Material y métodos. Se seleccionó una población de 200 reclusos de un total de 1.000.Las edades estaban comprendidas entre 18 y 69 años (media ± DE: 31,62 ± 9,93 años). La detección de anticuerpos contra el virus de la hepatitis C se realizó por duplicado mediante el método inmunoenzimático ELISA de IV generación y por el método de inmunoblot INNO-LIA HCV®, ambos de Innogenetic Lab (Bélgica). El ARN viral se detectó por la técnica de reacción en cadena de la polimerasa, previa transcripción inversa, RT-PCR. Resultados. La frecuencia obtenida con el método ELISA fue de 5% (10/200) y 3/200 (1,5%) individuos fueron positivos, a la vez, con los métodos de INNO-LIA y RT-PCR. Conclusiones. La prevalencia de la infección por el virus de la hepatitis C en esta población fue baja, lo que evidencia la baja circulación del virus en el reclusorio. El principal factor de riesgo para la adquisición de la infección, al parecer, es el uso de drogas intravenosas.Palabras clave: hepatitis C, prevalencia, prisioneros, Venezuela. Low prevalence of hepatitis C virus infection in a prisoner population from Maracaibo, VenezuelaIntroduction. The high risk behaviors observed in prison centers have favored the transmission of hepatitis C virus infection. The main risk factor to acquire hepatitis C virus infection seems to be the use of intravenous drugs. In Venezuela, the prevalence of the infection in these centers is unknown since studies of the hepatitis C virus there are lacking. Objective. The aim of this study was to determine the prevalence of hepatitis C virus and the risk factors involved in the transmission in prisoner populations. Material and methods. A sample of 200 prisoners was studied from Sabaneta Jail, Maracaibo, Venezuela. The ages were between 18-69 years (average ± DS: 31.6±9.9 years). Serum samples were tested by a fourth generation enzyme-linked immunosorbent assay ELISA and a confirmatory assay INNO-LIA. Both kits were from Innogenetic Laboratories N.V. (Belgium). Viral RNA was tested by the reverse transcription polymerase chain reaction technique (RT-PCR). Results. The ELISA assay determined a hepatitis C virus prevalence of 5.0% (10/200); 3/200 (1.5%) individuals were positive by both INNO-LIA and RT-PCR tests.

show abstract

Low prevalence of hepatitis C virus infection in Amerindians from Western Venezuela

Abstract: Previous studies have not found hepatitis C virus (HCV) infection in Amerindians from

Cited by 8 publications

References 16 publications

New natural variants of hepatitis B virus among Amerindians from Argentina with mainly occult infections

New natural variants of hepatitis B virus among Amerindians from Argentina with mainly occult infections

Hepatitis C virus infection in hemodialysis patients in Maracaibo, Venezuela

Baja prevalencia de la infección por el virus de la hepatitis C en una población de reclusos, Maracaibo, Venezuela

Contact Info

Product

Resources

About