“…37 A number of clinical reports provide practical advice about food allergy management. 43 There are many ways in which alcohol can induce allergic-type reactions, but Cardet et al 44 point out that a high percentage of patients with aspirin-exacerbated respiratory disease experience alcohol-induced nasal symptoms (75%) and wheeze/dyspnea (51%) that correlate with the severity of their aspirin-induced reactions. Patients with food allergies must worry about food proteins in medications and vaccines; Kelso 45 catalogued the foods and types of medication that are of concern, providing a very practical review.…”
This review highlights some of the research advances in anaphylaxis; hypersensitivity reactions to foods, drugs, and insects; and allergic skin diseases that were reported in the Journal in 2014. Studies on food allergy suggest worrisomely high rates of peanut allergy and food-induced anaphylaxis-related hospitalizations. Evidence is mounting to support the theory that environmental exposure to peanut, such as in house dust, especially with an impaired skin barrier attributed to atopic dermatitis (AD) and loss of function mutations in the filaggrin gene, is a risk factor for sensitization and allergy. Diagnostic tests are improving, with early studies suggesting the possibility of developing novel cellular tests with increased diagnostic utility. Treatment trials continue to show the promise and limitations of oral immunotherapy, and mechanistic studies are elucidating pathways that might define the degree of efficacy of this treatment. Studies have also provided insights into the prevalence and characteristics of anaphylaxis and insect venom allergy, such as suggesting that baseline platelet-activating factor acetylhydrolase activity levels are related to the severity of reactions. Advances in drug allergy include identification of HLA associations for penicillin allergy and a microRNA biomarker/mechanism for toxic epidermal necrolysis. Research identifying critical events leading to skin barrier dysfunction and the polarized immune pathways that drive AD have led to new therapeutic approaches in the prevention and management of AD.
“…37 A number of clinical reports provide practical advice about food allergy management. 43 There are many ways in which alcohol can induce allergic-type reactions, but Cardet et al 44 point out that a high percentage of patients with aspirin-exacerbated respiratory disease experience alcohol-induced nasal symptoms (75%) and wheeze/dyspnea (51%) that correlate with the severity of their aspirin-induced reactions. Patients with food allergies must worry about food proteins in medications and vaccines; Kelso 45 catalogued the foods and types of medication that are of concern, providing a very practical review.…”
This review highlights some of the research advances in anaphylaxis; hypersensitivity reactions to foods, drugs, and insects; and allergic skin diseases that were reported in the Journal in 2014. Studies on food allergy suggest worrisomely high rates of peanut allergy and food-induced anaphylaxis-related hospitalizations. Evidence is mounting to support the theory that environmental exposure to peanut, such as in house dust, especially with an impaired skin barrier attributed to atopic dermatitis (AD) and loss of function mutations in the filaggrin gene, is a risk factor for sensitization and allergy. Diagnostic tests are improving, with early studies suggesting the possibility of developing novel cellular tests with increased diagnostic utility. Treatment trials continue to show the promise and limitations of oral immunotherapy, and mechanistic studies are elucidating pathways that might define the degree of efficacy of this treatment. Studies have also provided insights into the prevalence and characteristics of anaphylaxis and insect venom allergy, such as suggesting that baseline platelet-activating factor acetylhydrolase activity levels are related to the severity of reactions. Advances in drug allergy include identification of HLA associations for penicillin allergy and a microRNA biomarker/mechanism for toxic epidermal necrolysis. Research identifying critical events leading to skin barrier dysfunction and the polarized immune pathways that drive AD have led to new therapeutic approaches in the prevention and management of AD.
“…In some countries, school staff are reported to have a low level of preparedness to prevent and manage food-induced allergic reactions [ 117 ]. Guidelines outlining a standardized approach to risk management of patients with food-induced allergic reactions in schools and other community settings have been developed; however, RCTs of the effectiveness of the interventions are needed to strengthen the evidence base for the recommendations [ 118 ].…”
The World Allergy Organization (WAO) Guidelines for the assessment and management of anaphylaxis provide a unique global perspective on this increasingly common, potentially life-threatening disease. Recommendations made in the original WAO Anaphylaxis Guidelines remain clinically valid and relevant, and are a widely accessed and frequently cited resource. In this 2015 update of the evidence supporting recommendations in the Guidelines, new information based on anaphylaxis publications from January 2014 through mid- 2015 is summarized. Advances in epidemiology, diagnosis, and management in healthcare and community settings are highlighted. Additionally, new information about patient factors that increase the risk of severe and/or fatal anaphylaxis and patient co-factors that amplify anaphylactic episodes is presented and new information about anaphylaxis triggers and confirmation of triggers to facilitate specific trigger avoidance and immunomodulation is reviewed. The update includes tables summarizing important advances in anaphylaxis research.
“…Poorly developed teachers’ competences for managing children’s allergies can pose a significant problem to the wellbeing of children in the preschool and school environments. Several studies ( 7 , 8 , 9 , 10 , 11 , 12 ), including the Europreval study ( 13 ), have revealed a low level of preparedness for managing children at risk of anaphylaxis in kindergartens and schools. The importance of the knowledge of school personnel in recognising children’s allergic reactions and providing first aid is pointed out in recommendations of the EAACI (European Academy of Allergology and Clinical Immunology) ( 1 , 2 ) and others ( 14 , 15 ).…”
IntroductionPoorly developed teachers’ competences for managing children’s allergies can pose a significant problem for the wellbeing of children in the preschool and school environment. The purpose of this study is to explore the attitudes and theoretical understanding of the management of allergic reactions in children among future teachers.MethodsA total of 572 future teachers participated in the study, 56% of whom were in the 1st year of undergraduate educational programmes, while 44% were in the 4th year. The participants answered the Teachers’ Health Competences Development – Allergy Questionnaire.ResultsThe future teachers showed positive attitudes towards learning more about different child health issues. There was an average understanding of managing allergic reactions in children (59.4%; SD=16.1% success), with no statistically significant difference regarding the duration of education, science background or the students’ self-allergy. There was, however, a statistically significant difference in achievement scores between future teachers in different educational programmes (F(3,568)=6.4, p≤.000). A subgroup of future teachers exposed to basic allergy education in the 1st year and tested again in the 4th year showed significantly better knowledge (Mann-Whitney
U=83.0; p=.008).ConclusionThe duration of future education, science background and self-allergy did not influence the level of knowledge regarding the management of allergic reactions in children. A basic educational programme in allergy management had a positive effect on future teachers’ knowledge of managing allergic reactions in children. Our study indicates that all future teachers should be included in specific educational programmes in order to develop adequate health competences.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.