Low Prealbumin Level Is a Risk Factor for Microvascular Free Flap Failure

Predictive Factors for Preoperative Percutaneous Endoscopic Gastrostomy Placement

“…[1][2][3][4][5][6][7][8][9][10][11][12] Based on this, 8 specific parameters were prospectively included for study. These included: body mass index, prealbumin, albumin, smoking history, presence of comorbidities [including coronary artery disease (CAD), chronic obstructive pulmonary disease (COPD), and diabetes mellitus (DM)], age, use of microvascular reconstruction, and location of defect (cervicofacial, skull base, oral cavity, oromandibular, and pharyngoesophageal).…”

“…Despite the lack of a robust univariate correlation and the poor performance of the multivariate regression, the original 8 variables were incorporated into the scoring system because of previous work showing their association with malnutrition. 2,9,11,[13][14][15][16][17] The ideal cutoff of the full screening tool was determined to be greater than or equal to 4, which yielded a sensitivity of 83% and specificity of 61%. The positive predictive value (PPV) of this tool is 59% and the negative predictive value is 84%.…”

“…This is critical to successful reconstruction, because it was shown that a decreased preoperative prealbumin level is associated with an increased rate of free flap failure. 11 Placing a PEG in every patient undergoing head and neck reconstruction, however, is also not warranted, because some of these patients never require one.…”

Value of the Post-Operative CT in Predicting Delayed Flap Failures Following Head and Neck Cancer Surgery

“…These include patient age, nutritional state, body mass index, diabetes mellitus, bleeding tendency, smoking, previous radiation therapy, location and stage of primary tumor, type of flap reconstruction, duration of anesthesia, and serum C-reactive protein level (12345678910). …”

Assessment of preoperative and postoperative prealbumin in thoracic surgery – a two months experience in a Romanian university hospital / Evaluarea preoperatorie şi postoperatorie a prealbuminei în chirurgia toracică - experiența de 2 luni a unui spital universitar din România

“…These include orthopaedics, abdominal surgery, head and neck surgery, neurosurgery, where poor nutritional status leads to a higher risk of infection, increased rate of failure of surgery or worsen the long-term outcome. The methods used for detecting patients at risk included serologic parameters, especially the use of prealbumin, clinical measurements, including hand-grip or nutritional risk scores (3)(4)(5)(6)(7).…”