Low permeability biomedical polyurethane nanocomposites

Xu, Riwei; Manias, Evangelos; Snyder, Alan J.; Runt, James

doi:10.1002/jbm.a.10377

Cited by 92 publications

(49 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Y-axis is amount of substance eluting. and properties, 4,16,30 and ultrasound has been seen in this laboratory to result in damage and scission of the PEU chain. Thus, the current study and that of Han et al have almost certainly been conducted on significantly different polymer systems and thus cannot be readily compared.…”

Section: Silicate Dispersionmentioning

confidence: 96%

In vitro fibroblast response to polyurethane organosilicate nanocomposites

Styan¹,

Martin²,

Poole‐Warren³

2007

J Biomedical Materials Res

View full text Add to dashboard Cite

The term nanocomposite refers to organic:inorganic composites where one phase, typically the inorganic phase, has dimensions on the nanoscale. Several authors have noted the potential benefit of biomedical application of nanocomposite technology, and have suggested using quaternary ammonium compounds (QAC) as an organic modification to enhance dispersion of nanoparticles within polymer matrices. This study aimed to examine fibroblast responses in vitro to a range of nanocomposites using different organic modifiers. Composite materials were prepared from a polyether urethane (PEU) and various unmodified and organically modified montmorillonite (MMT) nanoparticles. QAC and amino undecanoic acid (AUA) modified-MMT were added to PEU at loadings ranging from approximately 1 to 15 wt %. Composites with organically modified QAC and AUA particles displayed partially exfoliated and intercalated silicate morphology, respectively. Nanocomposites showed increases in ultimate tensile properties for materials with lower QACMMT loadings. However QAC was shown to significantly inhibit cell growth following release from PEU-QACMMT under extraction conditions mimicking those of the physiological environment. Materials containing silicate modified using AUA were cytocompatible. The results of this study suggest that QAC may be unsuitable as organic modifiers for nanoparticles destined for biomedical use. Alternative modifiers based on AUA confer equivalent dispersion and are of low toxicity.

show abstract

Section: Silicate Dispersionmentioning

confidence: 96%

In vitro fibroblast response to polyurethane organosilicate nanocomposites

Styan¹,

Martin²,

Poole‐Warren³

2007

J Biomedical Materials Res

View full text Add to dashboard Cite

show abstract

“…The second maximum degradation was increased more as compared to the first maximum degradation temperature. This may be due to better compatibility of the soft segment with clay and the initiation of the formation of char [2,6], which hinders the polymeric material from the exposure to heat, increasing the thermal stability.…”

Section: Tgamentioning

confidence: 99%

“…Incorporation of nanofillers including layered silicates improves their mechanical [1][2][3], thermal [4,5] and barrier [5][6][7][8][9] properties as compared to the pristine PU. Elastomeric polyurethane-clay nanocomposite (PUCN) was first reported by Wang and Pinavaia [1], who observed that montmorilonite clay exchanged with long-chain onium ions has very good compatibility with several polyols commonly used for the synthesis of PUs.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and Characterization of Elastomeric Polyurethane-Laponite Nanocomposite

Mishra

Chattophadyay

Nando

et al. 2008

Designed Monomers and Polymers

View full text Add to dashboard Cite

Polyurethanes (PU) are a group of versatile polymers finding a lot of engineering uses due to their favorable and tunable properties and processing advantages. Although considerable amount of work has been reported on the polyurethane-montmorilonite nanocomposite, there is not much literature available on the polyurethane-laponite clay nanocomposite. In this paper, we report the modification of laponite clay with dodecylamine hydrochloride by an ion-exchange process and in situ preparation of polyurethane-laponite clay nanocomposites. Clay incorporation into the polyurethane matrix increased the storage modulus and this trend continues with an increase in clay loading. Thermal stability of the composites was also increased with the clay loading. It was found that modified clay shows a tendency to be preferentially associated with the soft segment of polyurethane; however, the hard domain ordering gets significantly prejudiced at a lower clay loading. On the other hand, at higher clay loading, a nucleating tendency of clay aggregate was observed. The change in length scale of clay aggregation is demonstrated with SEM fractographs of the PU-clay nanocomposites.

show abstract

“…17 PU/MMT nanocomposites have been synthesized and characterized extensively ever since they were initially synthesized with MMT, in which Na þ or Ca 2þ ions residing initially in the interlayers were exchanged with alkyl ammonium ions to expand the silicate layer spacing. 18 The effects of silicate layers on the mechanical, [19][20][21] thermal, [22][23][24] and diffusional [25][26][27] properties of PU nanocomposites have been studied in many works. If expanded MMT is used in the PU nanocomposite, the breaking strength and modulus have been reported to be enhanced as much as 600 19 and 300%, 23 respectively, and resistance to the thermal degradation was significantly increased.…”

Section: Introductionmentioning

confidence: 99%

Synthesis and characterization of in situ polymerized segmented thermoplastic elastomeric polyurethane/layered silicate clay nanocomposites

Choi

Anandhan

Youk

et al. 2006

J of Applied Polymer Sci

View full text Add to dashboard Cite

Nanocomposites based on thermoplastic elastomeric polyurethane (TPU) and layered silicate clay were prepared by in situ synthesis. The properties of nanocomposites of TPU with unmodified clay were compared with that of organically modified clay. The nanocomposites of the TPU and organomodified clay showed better dispersion and exhibited superior properties. Exfoliation of the clay layers was observed at low organoclay contents, whereas an intercalated morphology was observed at higher clay contents. As one of major purposes of this study, the effect of the silicate layers in the nanocomposites on the order-disorder transition temperature (T ODT ) of the TPU was evaluated from the intensity change of the hydrogen-bonded and free carbonyl stretching peaks and from the peak position change of the NÀ ÀH bending peak. The presence of the organoclay increased T ODT by approximately 108C, which indicated improved stability in the phase-separated domain structure. The layered silicate clay caused a tremendous improvement in the stiffness of the TPU; meanwhile, a reduction in the ultimate elongation was observed.

show abstract

Low permeability biomedical polyurethane nanocomposites

Cited by 92 publications

References 24 publications

In vitro fibroblast response to polyurethane organosilicate nanocomposites

In vitro fibroblast response to polyurethane organosilicate nanocomposites

Synthesis and Characterization of Elastomeric Polyurethane-Laponite Nanocomposite

Synthesis and characterization of in situ polymerized segmented thermoplastic elastomeric polyurethane/layered silicate clay nanocomposites

Contact Info

Product

Resources

About