Low melting point metal-based flexible 3D biomedical microelectrode array by phase transition method

Guo, Shengxin; Lin, Rongzan; Wang, Lei; Lau, Shinying; Wang, Qian; Liu, Ran

doi:10.1016/j.msec.2019.02.015

Cited by 12 publications

(11 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Metals can be adopted to fabricate microneedle arrays due to their good strength. Guo et al [ 26 ] took some low melting alloys (Bi/In/Sn/Zn alloy, melting point only 57.5 °C) to make a flexible microneedle electrode based on PDMS (see Figure 4 ). The microneedle array was formed by dropping molten metal droplets directly onto the PDMS substrate.…”

Section: Invasive Microneedle Electrodesmentioning

confidence: 99%

“… ( a )–( d ) Schematic illustration of the fabrication process of multi-channel flexible microelectrode array device. ( e ) Image of multi-channel flexible microelectrode [ 26 ]. …”

Section: Figurementioning

confidence: 99%

“… Anisotropic etching Lin [ 25 ] Self-stabilized diamond-shaped microneedles array Silicon, Au Invasive EEG electrode The length of microneedles is about 250 μm, the impedance of electrode is about 5 kΩ at 10 Hz. Anisotropic etching Guo [ 26 ] Low melting point metal-based flexible 3D microneedles array PDMS, metal Invasive EEG electrode The electrode has a flexible PDMS substrate, was based on low melting point metals, and it can be stretched to a maximum of 42% before it becomes non-conducting. Phase transition method, 3D printing Ren [ 27 ] Flexible microneedle array electrode for bio-signal monitoring Epoxy novolac resin, iron particles, Ti/Au, polyimide Invasive ECG electrode Microneedle array can be one-step drawn from the droplet array of curable magnetorheological fluid under the assist of external magnetic field.…”

Section: Table A1mentioning

confidence: 99%

See 2 more Smart Citations

Dry Electrodes for Human Bioelectrical Signal Monitoring

Zhao

Dong

et al. 2020

Sensors

119

View full text Add to dashboard Cite

Bioelectrical or electrophysiological signals generated by living cells or tissues during daily physiological activities are closely related to the state of the body and organ functions, and therefore are widely used in clinical diagnosis, health monitoring, intelligent control and human-computer interaction. Ag/AgCl electrodes with wet conductive gels are widely used to pick up these bioelectrical signals using electrodes and record them in the form of electroencephalograms, electrocardiograms, electromyography, electrooculograms, etc. However, the inconvenience, instability and infection problems resulting from the use of gel with Ag/AgCl wet electrodes can’t meet the needs of long-term signal acquisition, especially in wearable applications. Hence, focus has shifted toward the study of dry electrodes that can work without gels or adhesives. In this paper, a retrospective overview of the development of dry electrodes used for monitoring bioelectrical signals is provided, including the sensing principles, material selection, device preparation, and measurement performance. In addition, the challenges regarding the limitations of materials, fabrication technologies and wearable performance of dry electrodes are discussed. Finally, the development obstacles and application advantages of different dry electrodes are analyzed to make a comparison and reveal research directions for future studies.

show abstract

Section: Invasive Microneedle Electrodesmentioning

confidence: 99%

“… ( a )–( d ) Schematic illustration of the fabrication process of multi-channel flexible microelectrode array device. ( e ) Image of multi-channel flexible microelectrode [ 26 ]. …”

Section: Figurementioning

confidence: 99%

Section: Table A1mentioning

confidence: 99%

See 1 more Smart Citation

Dry Electrodes for Human Bioelectrical Signal Monitoring

Zhao

Dong

et al. 2020

Sensors

119

View full text Add to dashboard Cite

show abstract

“…ISF contains rich physiological/pathological information than ever envisaged [ 197 ], in the meantime, the MN-based biosensor can serve as a portal for the pain-free acquisition of valuable information. Besides, recent research efforts have led to the emergence of advanced microfabrication and biophotonics that facilitate the manufacture of MNs [ 37 , 39 , 198 ]. More complicated MN platforms that integrate electrochemical biosensors [ 157 , 169 , 181 ] or biofuel cells [ 37 ] (harvesting energy from biofluids, such as sweat and ISF, to power wearable platforms) have been manufactured.…”

Section: Key Analytes and Wearable Biosensing Platformsmentioning

confidence: 99%

“…An excellent example can be found in wearable/ambulatory healthcare monitoring and sports analytics harnessing skin-interfaced wearable biosensors [ 15 , 23 ]. Although this field is still in its infancy, the fundamentals of it are exceptionally strong: in the past decade, the wearable LOC devices gradually integrated with well-established techniques, including biocompatible materials [ 24 , 25 ], flexible electronics [ 26 , 27 , 28 , 29 , 30 ], optical/electrochemical sensors [ 14 , 26 , 31 , 32 ], microfluidics [ 21 , 33 , 34 , 35 ], near-field communications (NFC) [ 36 ], pain-free microneedles [ 37 , 38 , 39 , 40 ], as well as big data and cloud computing [ 14 , 41 , 42 ].…”

Section: Introductionmentioning

confidence: 99%

Recent Progress in Wearable Biosensors: From Healthcare Monitoring to Sports Analytics

Feng

Huang

et al. 2020

Biosensors

View full text Add to dashboard Cite

Recent advances in lab-on-a-chip technology establish solid foundations for wearable biosensors. These newly emerging wearable biosensors are capable of non-invasive, continuous monitoring by miniaturization of electronics and integration with microfluidics. The advent of flexible electronics, biochemical sensors, soft microfluidics, and pain-free microneedles have created new generations of wearable biosensors that explore brand-new avenues to interface with the human epidermis for monitoring physiological status. However, these devices are relatively underexplored for sports monitoring and analytics, which may be largely facilitated by the recent emergence of wearable biosensors characterized by real-time, non-invasive, and non-irritating sensing capacities. Here, we present a systematic review of wearable biosensing technologies with a focus on materials and fabrication strategies, sampling modalities, sensing modalities, as well as key analytes and wearable biosensing platforms for healthcare and sports monitoring with an emphasis on sweat and interstitial fluid biosensing. This review concludes with a summary of unresolved challenges and opportunities for future researchers interested in these technologies. With an in-depth understanding of the state-of-the-art wearable biosensing technologies, wearable biosensors for sports analytics would have a significant impact on the rapidly growing field—microfluidics for biosensing.

show abstract

Current Status and Outlook of Low‐Melting‐Point Metals in Biomedical Applications

Mao,

Kim,

Seo

2023

Adv Funct Materials

View full text Add to dashboard Cite

In recent years, low‐melting‐point metals including liquid metals, exhibiting outstanding physical and chemical properties such as excellent thermal and electrical conductivity, high surface tension, and biocompatibility, have garnered increasing attention from researchers. The melting point of such metals profoundly influences their properties and determines their range of applications, and comprehending the characteristics and properties of low‐melting‐point metals is crucial for their future applications. Although studies related to liquid metals are growing exponentially in particular, reports exploring the properties and applications of low‐melting‐point metals from the perspective of the melting point are still in their early stages. This review aims to comprehensively summarize the key properties and relevant applications of current low‐melting‐point metals described in recent studies, focusing on gallium‐ and bismuth‐based metal alloys. In addition, this review discusses the opportunities and challenges associated with low‐melting‐point metals, and it is anticipated that this review will contribute to the advancement of low‐melting‐point materials in the fields of flexible electronics and biomedicine, particularly for biomedical applications.

show abstract

Low melting point metal-based flexible 3D biomedical microelectrode array by phase transition method

Cited by 12 publications

References 13 publications

Dry Electrodes for Human Bioelectrical Signal Monitoring

Dry Electrodes for Human Bioelectrical Signal Monitoring

Recent Progress in Wearable Biosensors: From Healthcare Monitoring to Sports Analytics

Current Status and Outlook of Low‐Melting‐Point Metals in Biomedical Applications

Contact Info

Product

Resources

About