Low melting mixture glycerol:proline as an innovative designer solvent for the synthesis of novel chromeno fused thiazolopyrimidinone derivatives: An excellent correlation with green chemistry metrics

Mohire, Priyanka P.; Chandam, Dattatray; Patil, Reshma; Patravale, Ajinkya A.; Ghosh, Jai S.; Deshmukh, M. B.

doi:10.1016/j.molliq.2019.03.058

Cited by 15 publications

(2 citation statements)

References 56 publications

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“…From the standpoint of Green Chemistry, it is desirable to recycle the reaction system to reduce the discharge of materials in the environment, and this aspect is presently of great interest. 71 To address this issue, we chose [ChCl]:[EG] as the solvent system, and we attempted its reuse. After the first reaction, 1 mL of water was added to the reaction mixture that was washed with ethyl acetate (3 × 1 mL).…”

Section: Analogous Considerations Can Be Drawn Comparing Results Corr...mentioning

confidence: 99%

A Joint Action of Deep Eutectic Solvents and Ultrasound to Promote Diels–Alder Reaction in a Sustainable Way

Marullo

Meli

D’Anna

2020

ACS Sustainable Chem. Eng.

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The need to reduce environmental impact of chemical processes has induced a surge of attention in the choice of solvent and methodologies to carry them out. In this context, we studied the Diels–Alder reaction using N-ethylmaleimide as dienophile and changing the nature of the diene in deep eutectic solvents (DES) under both conventional heating and ultrasonic activation. DES obtained by the combination of different hydrogen bond acceptors and donors allowed assessing the role played by solvent nature. DES proved suitable solvent media for the target reaction, allowing higher yields and faster reactions compared to conventional organic solvents. The trend of yields, both in silent and under ultrasound irradiation, was rationalized considering solvent viscosity and structural organization. In particular, thanks to a combined approach of resonance light scattering (RLS) and 1H NMR investigation, a relationship between performance of the reaction and thickness and strength of the hydrogen bond network of the solvent was identified. Moreover, DES could be recycled up to eight times without any loss in yield. Using ultrasonic activation in combination with DES proved beneficial providing good yields in drastically reduced reaction times. From the standpoint of Green Chemistry, the combined use of ultrasound and DES allowed reducing energy consumption by more than 99% compared with silent reactions and proved beneficial for the scalability of the process.

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Section: Analogous Considerations Can Be Drawn Comparing Results Corr...mentioning

confidence: 99%

A Joint Action of Deep Eutectic Solvents and Ultrasound to Promote Diels–Alder Reaction in a Sustainable Way

Marullo

Meli

D’Anna

2020

ACS Sustainable Chem. Eng.

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“…[14] 5 three-component reaction of 4-hydroxycoumarin, benzaldehydes, and 2-mino 5-methyl thiazole. [15] 6 The multi-component reaction of 2-aminobenzothiazoles, 4-hydroxy-6-methyl-2-pyrone/4-hydroxycoumarin, and aryl aldehydes. [16] Today, the tendency to produce and use of nanomaterials is increasing due to the interesting features of these materials.…”

Section: Introductionmentioning

confidence: 99%

MgO nanopowders catalyzed synthesis of pyrano[4,3‐d]thiazolo[3,2‐a]pyrimidine derivatives

Khalaj

Mousavi-Safavi

Farahani

et al. 2020

Applied Organom Chemis

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A cubic phase of pure MgO nanopowders was prepared in an aqueous solution containing freshly squeezed orange juice with pulp and characterized by X‐ray diffraction (XRD), field emission scanning electron microscopy (FE‐SEM), energy‐dispersive X‐ray spectroscopy (EDS), and Fourier transform infrared (FT‐IR) spectroscopic techniques. The catalytic potential of MgO nanopowders was evaluated in preparation of pyrano[4,3‐d]thiazolo[3,2‐a]pyrimidine and chromeno[4,3‐d]thiazolo[3,2‐a]pyrimidines derivatives using the three simple methods including thermal, ultrasonic irradiation, and high‐speed ball milling (HSBM) technique under solvent‐free conditions. All products were successfully formed in high yields.

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Box–Behnken design optimisation of a green novel nanobio-based reagent for rapid visualisation of latent fingerprints on wet, non-porous substrates

et al. 2021

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Low melting mixture glycerol:proline as an innovative designer solvent for the synthesis of novel chromeno fused thiazolopyrimidinone derivatives: An excellent correlation with green chemistry metrics

Cited by 15 publications

References 56 publications

A Joint Action of Deep Eutectic Solvents and Ultrasound to Promote Diels–Alder Reaction in a Sustainable Way

A Joint Action of Deep Eutectic Solvents and Ultrasound to Promote Diels–Alder Reaction in a Sustainable Way

MgO nanopowders catalyzed synthesis of pyrano[4,3‐d]thiazolo[3,2‐a]pyrimidine derivatives

Box–Behnken design optimisation of a green novel nanobio-based reagent for rapid visualisation of latent fingerprints on wet, non-porous substrates

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