Low meats and sweets diet attenuates the effect of overweight duration on glucose levels among Filipino women

Abstract

Overweight (OW) duration and diet affect glucose levels. We examined whether diet modified the effect of OW duration on fasting glucose and having impaired fasting glucose or type 2 diabetes (IFG/DM: FG>;=110mg/dL) in 1,887 women (ages 35–68y) in the 2005 Cebu Longitudinal Health and Nutrition Survey. OW (BMI>;=25kg/m2) duration was categorized as >;=10 y (25%), < 10 y (17%), had a history but not currently OW (10%) and never OW (48%). Using factor analysis, we identified 3 diet patterns: meats/sweets, vegetables/grains, and processed seafoods. Mean FG was 99.6 mg/dL; 14% had IFG/DM. For FG, linear regression results showed significant interaction between OW duration and the meats/sweets pattern (LR test p<0.04). OW duration was not significantly associated with FG among women who consumed low meats/sweets (lowest quartile): 1.6 (−10.1, 13.2) [COEFF (95% CI)] for women OW <10 yrs and 2.6 (−10.8,15.9) for women OW >;10yrs. For women who consumed higher amounts of meats/sweets, compared to never OW women, FG was 4.5 (− 2.0,11.4) and 18.8 (11.0, 26.5) mg/dL higher for women OW < 10y and OW >;=10y, respectively. Similarly, we found increased effect of OW duration on having IFG/DM among women who consumed greater meats/sweets. Results underscore the benefit of controlling meats and sweets consumption, especially among those who have been chronically OW. R01TW008288