Low m6A modification-mediated upregulation of PLAC8 promotes trophoblast cell invasion and migration in preeclampsia
Yajuan Zhang,
Xiaoguang Guo,
Zhimin Chen
et al.
Abstract:Background
The main symptoms of preeclampsia (PE), a specific ailment that develops during pregnancy, are proteinuria and hypertension. The pathological root of the onset and progression of PE is widely regarded as abnormal placental trophoblast cell function. This study aimed to look into the character and mechanism of Placenta-specific 8 (PLAC8) in trophoblast cell invasion and migration.
Methods
Expressions of PLAC8 and AlkB homologue 5 (ALKBH5)… Show more
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