The challenges of THz electronics in CMOS technologies for THz sensing and communication applications are addressed in this work, focusing on device-level design to system integration approaches. State-of-the-art THz circuits, components, design methodologies, and system demonstration were proposed, including a 40-nm-CMOS transistor layout design using an electromagnetic modeling approach, a 340-GHz higher-order-mode high-gain dielectric resonator antenna, a 340-GHz CMOS heterodyne receiver, a 340-GHz heterogeneously-integrated THz transmitter with 2×25 antennas, a THz heterogeneously-integrated platform with low-loss single-band, dual-band, and broadband interconnects, and a THz transmissive imaging system with a spatial resolution of 1.4 mm at 336 GHz.