Low-Level-Lasertherapie

Baltzer, A. W. A.; Stosch, Daniel; Seidel, Florian; Ostapczuk, Martin

doi:10.1007/s00393-017-0309-1

Cited by 8 publications

(4 citation statements)

References 31 publications

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“…Adverse drug effects (osteoporosis, growth retardation secondary to glucocorticoids, etc.) are important considerations for treating juvenile RA 36 . Physiotherapeutic rehabilitation is therefore important in juvenile RA, as the disease and treatments may influence growth and development.…”

Section: Discussionmentioning

confidence: 99%

Effects of Laser Therapy on Rheumatoid Arthritis

Chia¹,

Chang²,

Hou³

2021

Am J Phys Med Rehabil

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Section: Discussionmentioning

confidence: 99%

Effects of Laser Therapy on Rheumatoid Arthritis

Chia¹,

Chang²,

Hou³

2021

Am J Phys Med Rehabil

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“…Recent studies have tended to be more positive with those treated with laser therapy and exercise faring better than those treated with exercise alone in terms of pain measurements as well as function [34,35]. These studies suggest that LLLT in combination with standard physiotherapy could provide advantages over standard therapy, and it shows potential as a non-invasive, safe and cost-efficient treatment modality [36]. Once again, however, evidence is lacking regarding long-term effects and whether the cellular effects seen modify disease progression.…”

Section: Laser Therapymentioning

confidence: 99%

Non-Surgical Regional Therapy for Osteoarthritis: An Update and Review of the Literature

Wilson-Morkeh¹,

Mackworth‐Young²

2021

Recent Advances in Bone Tumours and Osteoarthritis

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Osteoarthritis (OA) is the most common joint condition worldwide. It can lead to chronic debilitating symptoms that can be definitively managed with surgical techniques at times. More frequently however, either due to age, extent of disease or patient choice, non-surgical approaches are preferred. They include topical therapies such as thermotherapy, ultrasound, laser treatment, non-steroidal anti-inflammatory drugs (NSAIDs) and capsaicin cream. Injections are another technique often implemented. These consist of intra-articular (IA) corticosteroid or hyaluronan injections, trigger point injections and subcutaneous sodium salicylate. Acupuncture and various types of external support are also widely used. This chapter examines the latest evidence and summarises the role of the various regional treatments available for use in the management of OA.

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“…Studies have shown that LLLT increases the expression of VEGF gene and protein in smooth muscle cells, fibroblasts, cardio-myocytes and cardiac myocytes (21)(22)(23). Besides, LLLT can increase the expression of IL-6 in some cells including keratinocytes (24).…”

Section: Introductionmentioning

confidence: 99%

The Effect of Low‐level Laser Therapy on VEGF, IL‐6 Expression and Viability of Oral Squamous Cell Carcinoma Cells

Mansourian

Pourshahidi

Manshadi

et al. 2022

Photochem & Photobiology

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Low-level laser therapy has shown successful results in the prevention and treatment of oral mucositis. One of the concerns about low-level lasers is their effects on remaining malignant cells in the area. Interleukin-6 is a multifunctional cytokine that plays an important role in a wide range of biological activities in increasing tumor functions, decreasing survival and resistance to chemo-radiotherapy. Vascularendothelial growth factor increases tumor vascularization. It has been shown in the previous studies that LLLT can cause an increase of IL-6 and VEGF in some cells. The present thesis aims to study the effects of LLLT on IL-6 and VEGF expression, as well as cell viability on OSCC cells. Tumorigenic cells of an oral squamous cell carcinoma cell line were irradiated with 3 different diode lasers, and were compared to the control group (660 nm-200 mW-4 J cm À2 , 810 nm-200 mW-4 J cm À2 , 940 nm-200 mW-4 J cm À2 ). MTT assay, ELISA and RT-PCR were used to measure cell viability, IL-6 and VEGF expression. Cell viability of all laser-irradiated groups was significantly lower than the control group. VEGF expression increased in laser-irradiated groups. This was only significant in the 810 nm group. IL-6 protein secretion was significantly higher in all laser-irradiated groups compared to the control group.

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Low-Level-Lasertherapie

Abstract: LLLT shows potential as an effective, noninvasive, safe and cost-efficient means to treat and prevent a variety of acute and chronic musculoskeletal conditions. Further randomized controlled studies, however, are required to confirm this positive assessment.

Cited by 8 publications

References 31 publications

Effects of Laser Therapy on Rheumatoid Arthritis

Effects of Laser Therapy on Rheumatoid Arthritis

Non-Surgical Regional Therapy for Osteoarthritis: An Update and Review of the Literature

The Effect of Low‐level Laser Therapy on VEGF, IL‐6 Expression and Viability of Oral Squamous Cell Carcinoma Cells

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