Low-level laser therapy is effective in controlling postoperative pain in lower third molar extractions: a systematic review and meta-analysis

Barros, Daiane Domingos de; Catão, Josefa Simere dos Santos Barros; Ferreira, Alieny Cristina Duarte; Simões, Thamyres Maria Silva; Almeida, Renata de Albuquerque Cavalcanti; Catão, Maria Helena Chaves de Vasconcelos

doi:10.1007/s10103-021-03470-3

Cited by 15 publications

(18 citation statements)

References 36 publications

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“…Finally, 19 eligible meta-analyses were retrieved (Figure 1). Seven types of complementary interventions were identified among the retrieved meta-analyses including PRF application [12,[27][28][29][30][31][32], LLLT [33], [6,[34][35][36][37], Kinesio taping [8,38], cryotherapy [11], surgical drainage [9], ozone therapy [7], and hyaluronic acid application [10].…”

Section: Identification Of the Eligible Meta-analysesmentioning

confidence: 99%

“…e aggregate sample size varied from 132 to 1060 patients. Only two systematic reviews used Cochrane RoB tool-2 [8,31] and others used the Cochrane RoB tool-1 [13]; [7,[9][10][11][12]. e total number of included RCTs ranged from 4 to 21.…”

Section: Characteristics Of Selected Meta-analyses For Quantitativementioning

confidence: 99%

“…On the other hand, nonpharmacological complementary interventions are proposed to enhance pain relief, and reduce analgesic use, mitigating the unwanted e ects and contraindications of allopathic medications [6][7][8][9][10][11][12]. is goal is especially important in reducing or eliminating the use of opioid analgesics.…”

Section: Introductionmentioning

confidence: 99%

“…ey include the application of low-level laser therapy (LLLT) [13], cryotherapy [11], application of platelet-rich fibrin (PRF) [12], application of hyaluronic acid [10], ozone therapy [7], application of drainage [9], and kinesio taping (sports tapes) [8].…”

Section: Introductionmentioning

confidence: 99%

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Nonpharmacological Complementary Interventions for the Management of Pain after Third Molar Surgery: An Umbrella Review of Current Meta-Analyses

Firoozi

Falci

Kim

et al. 2022

Pain Research and Management

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Objectives. To provide a nonbiased, complete assessment of what the evidence from meta-analyses informs us about complementary and nonpharmacological treatment options for the management of pain after third molar surgery, as well as highlight any discordancy, gaps, or lack of evidence among meta-analyses. Methods. The quality of the included systematic reviews was assessed using the ROBIS tool. Corrected covered area (CCA) was calculated for pairs of similar meta-analyses to identify the amount of overlap. Reviews that were the most recent, comprehensive, and had adequate quality were considered for analyses when reviews showed a high overlap. In cases with a low amount of overlap among meta-analyses, all eligible studies were included. Also, citation matrices were constructed to address overlap. A network meta-analytical approach was adopted to rank different interventions. Results. Ten meta-analyses were included for quantitative synthesis. The quantitative analysis revealed that platelet-rich fibrin and its derivatives as well as ozone therapy reduce early and late pain better than the other complementary interventions compared to control (no complementary intervention). Conclusions. Despite the shortcomings of included meta-analyses, consolidated evidence suggests that platelet-rich-fibrin and its derivatives as well as ozone therapy outperform the other nonpharmacological complementary interventions in reducing early and late postsurgical pain following third molar extraction. However, the results should be interpreted with caution due to an unclear risk of bias and lack of firm evidence in the included meta-analyses. Moreover, there is a need for a standard protocol for the application of nonpharmacological complementary interventions.

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Section: Identification Of the Eligible Meta-analysesmentioning

confidence: 99%

Section: Characteristics Of Selected Meta-analyses For Quantitativementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Nonpharmacological Complementary Interventions for the Management of Pain after Third Molar Surgery: An Umbrella Review of Current Meta-Analyses

Firoozi

Falci

Kim

et al. 2022

Pain Research and Management

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“…LLLT has been used in various oral conditions including lichen planus [19], burning mouth syndrome [20], recurrent herpes labialis [21], postherpetic neuralgia [22], temporomandibular joint disorders [23], accelerating orthodontic tooth movement [24], dry socket [25] and controlling postoperative pain after lower third molar extraction [26].…”

Section: Introductionmentioning

confidence: 99%

Effect Of Low-Level Laser Therapy On Inflammatory Sequеlae Of Impacted Mandibular Third Molar Surgery: A Single-Blind, Placebo-Controlled, Randomized Clinical Trial

Hamad

2022

Russ Open Med J

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Objective — Postoperative pain, facial swelling, and limitation of mouth opening are common sequеlae of lower third molar surgery. The objective of the study was to evaluate the effect of Low- level laser irradiation in controlling these sequеlae. Material and Methods — This randomized, single-blinded, split-mouth pilot study was carried out at the department of oral and maxillofacial surgery, university affiliated hospital, Erbil, Iraq. The study was conducted on 20 patients (13 males and 7 females), with a mean age of 26.3±7.4 years, who needed surgical removal of symmetrical bilateral impacted lower third molars. In each patient, one side was treated by low level laser and the other side was control. Laser irradiation was performed by postoperative single intraoral application of 940 nm laser beam at four points. Pain, trismus, and facial swelling were evaluated at the first, third, and seventh postoperative days. The data were analyzed using Mann–Whitney U test and unpaired t -test. Results — As compared to the control sides, low- level laser irradiated sides showed a significant reduction in visual analogue pain scales (VAS) during the first three postoperative days (P<0.05). The VAS scores of the laser treated sides were 4.46, 4.00, and 3.35 as compared to 6.58, 5.82, and 5.17 for the control sides. The swelling, and trismus were significantly reduced on the first and third postoperative days in the laser treated sides, as compared to the control sides (P<0.05). The facial measurements during the first and third postoperative days were 108.72 mm and 114.77 mm in the laser sides and 113.57 mm and 118.43 mm in the control sides. The degree of mouth opening during the first and third postoperative days were 33.48 mm and 30.37 mm in the laser sides and 27.93 mm and 25.58 mm in the control sides Conclusions — Single intraoral application of low- level laser is effective in reducing pain, swelling and trismus after mandibular third molar surgery. Therefore, it can be used as an adjuvant in controlling postoperative complications after lower third molar surgery.

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Clinical and thermographic evaluation after lower third molar extractions and the application of different photobiomodulation protocols: double-blind randomised clinical trial

de Paula,

de Andrade Fernandes,

Evangelista

et al. 2024

Clin Oral Invest

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Low-level laser therapy is effective in controlling postoperative pain in lower third molar extractions: a systematic review and meta-analysis

Cited by 15 publications

References 36 publications

Nonpharmacological Complementary Interventions for the Management of Pain after Third Molar Surgery: An Umbrella Review of Current Meta-Analyses

Nonpharmacological Complementary Interventions for the Management of Pain after Third Molar Surgery: An Umbrella Review of Current Meta-Analyses

Effect Of Low-Level Laser Therapy On Inflammatory Sequеlae Of Impacted Mandibular Third Molar Surgery: A Single-Blind, Placebo-Controlled, Randomized Clinical Trial

Clinical and thermographic evaluation after lower third molar extractions and the application of different photobiomodulation protocols: double-blind randomised clinical trial

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