Low-level laser therapy for the treatment of epidermolysis bullosa: A case report

Minicucci, Eliana Maria; Barraviera, Sílvia Regina Catharino Sartori; Miot, Hélio Amante; Almeida‐Lopes, Luciana

doi:10.3109/14764172.2010.502460

Cited by 15 publications

(11 citation statements)

References 27 publications

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“…In a study by Trelles & Allones, researchers found that the use of LED red light therapy led to significant improvements in patients' wounds, cutting healing time by one-half or one-third when compared to those not treated with LED 8 . Additionally, another study resulted in the conclusion that LLLT was effective in speeding up the healing process of patients' dystrophic epidermolysis bullosa 11 . Lastly, a final study showed some benefit in patients using LLLT to treat unresponsive skin ulcers 12 .…”

Section: Resultsmentioning

confidence: 98%

To evaluate the safety and efficiency of low level laser therapy (LLLT) in treating decubitus ulcers: a review

Ahmed¹

2015

Mechanisms for Low-Light Therapy X

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Introduction: Pressure sores (decubitus ulcer) are a serious problem in health care management, especially for middleaged to older people who are bed-ridden. Although preventative measures are used, the condition remains common and development of novel, improved treatment methods are desirable. This article reviews the application of laser-based methods, previously shown to be effective in accelerating wound-healing in animal models and in the treatment of decubitus ulcers in humans. Methods: About 23 scientific articles on the effect of low level laser therapy (LLLT) on wound healing in animals and humans from 2000-2014 were reviewed. Additionally, results of several randomized controlled trials (RCTs) were reviewed, and compared with other treatment methods available. Results: Whilst carefully controlled, laboratory-based animal studies indicated that LLLT can reduce healing time for several types of injuries, however similar studies in humans failed to demonstrate consistent beneficial effects in the clinical setting. An acceleration of decubitus ulcer healing has been occasionally found, although limited to certain wavelengths and sometimes only in combination with other types of therapies. Indeed, some of the clinical articles indicated that certain laser wavelengths can have detrimental effects on time of healing. Conclusions: To date, there remains no convincing evidence that LLLT has consistent medical benefit in treating decubitus ulcers. Caution should be applied when considering LLLT since only certain wavelengths utilized have shown beneficial effects. It is concluded that, more RCTs are needed since, there is no clinical justification for LLLT, alone or in combination with other methods, in treating decubitus ulcers.

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Section: Resultsmentioning

confidence: 98%

To evaluate the safety and efficiency of low level laser therapy (LLLT) in treating decubitus ulcers: a review

Ahmed¹

2015

Mechanisms for Low-Light Therapy X

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“…A FBM tem se mostrado eficiente no tratamento de diversas lesões. Estudos evidenciam resultados importantes no processo da cicatrização de feridas em pacientes diabéticos, queimaduras, epidermólise bolhosa, entre outras (Carvalho et al, 2016;Kazemikazemikoo et al, 2018;Minicucci et al, 2010).…”

Section: Discussionunclassified

Associação de diferentes abordagens da laserterapia de baixa potência no tratamento da deiscência cirúrgica de artroplastia do joelho

Freitas

Minicucci

Bragnato

et al. 2021

RSD

Self Cite

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O objetivo do trabalho foi demonstrar a associação da fotobiomodulação, terapia fotodinâmica, terapia a laser a vácuo, irradiação de sangue com laser transcutâneo e curativo gel de Polihexametileno Biguanida tópicos no tratamento de deiscências de artroplastia de joelho. A metodologia utilizada foi um relato de caso descritivo, com coleta de dados do tratamento da paciente por meio do prontuário eletrônico. Foram analisados os sinais e sintomas, apresentados pela paciente, bem como as características da ferida. Dessa forma, os protocolos utilizados foram prescritos de forma individualizada, garantindo um atendimento diferenciado para a paciente. Foi autorizado pelo comitê de ética e a paciente assinou o termo de consentimento livre e esclarecido. Os resultados demostraram que a associação de diferentes abordagens da fotobiomodulação foram eficazes na cicatrização completa da ferida. Após 8 dias, observamos uma diminuição da profundidade do leito, do eritema e da inflamação do tecido ao redor com delimitação das bordas da ferida; bem como o clareamento da pele. Por tratar-se de uma ferida crônica, infectada a cicatrização completa aconteceu em sessenta e três dias. Conclui-se que que a combinação da ação fotodinâmica com pressão negativa estimulando a vascularização e a oxigenação bem como a melhora das condições corporais com SVPBM, promoveu uma recuperação muito mais rápida do que cada ação individual.

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“…При поиске в библиографических базах данных найдена одна публикация клинического случая, в которой описано полное заживление язвы (7 см диаметром), существовавшей более 9 мес., у 22-летнего пациента с РДБЭ после двух процедур абляционного фракционного лазерного облучения [64].…”

Section: физиотерапияunclassified

Congenital Epidermolysis Bullosa: Peculiarities of Epidermis Regeneration and Methods of Treatment

Кубанов

Карамова

Albanova

et al. 2017

Vestnik dermatologii i venerologii

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Congenital epidermolysis bullosa is a group of hereditary skin diseases caused by mutations in the genes of structural proteins of the dermoepidermal junction of the skin, characterized by formation of blisters and erosions at the smallest mechanical trauma. In patients with severe subtypes of borderline and dystrophic epidermolysis bullosa there are long-term erosive and ulcerative defects with disruption of the healing process. Factors that impede healing include: malnutrition, anemia, pain, inactivity, local factors (presence of infection, prolonged inflammation, extensive nature of the lesion, absence of skin appendages in the affected area, deficiency or lack of formation of type VII collagen). Elimination of healing impeding factors is the main challenge in treatment of severe subtypes of bullous epidermolysis. Modern promising treatment techniques are at the stage of development and have not yet been introduced into clinical practice, and, as of today, skin care and optimal topical treatment with modern non-adhesive dressings remain the most widespread treatment methods that facilitate accelerated healing.

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Low-level laser therapy for the treatment of epidermolysis bullosa: A case report

Cited by 15 publications

References 27 publications

To evaluate the safety and efficiency of low level laser therapy (LLLT) in treating decubitus ulcers: a review

To evaluate the safety and efficiency of low level laser therapy (LLLT) in treating decubitus ulcers: a review

Associação de diferentes abordagens da laserterapia de baixa potência no tratamento da deiscência cirúrgica de artroplastia do joelho

Congenital Epidermolysis Bullosa: Peculiarities of Epidermis Regeneration and Methods of Treatment

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