2020
DOI: 10.1016/j.bbrc.2020.03.142
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Low-intensity pulsed ultrasound regulates proliferation and differentiation of neural stem cells through notch signaling pathway

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Cited by 23 publications
(27 citation statements)
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References 35 publications
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“…Tan et al [ 7 ] listed recent studies regarding the action of LIPUS on various neural stem cells and concluded that LIPUS can stimulate stem cells in vitro , promote stem cell proliferation, differentiation, and migration, and maintain stem cell activity. The findings of Wu et al [ 8 ] suggested that LIPUS regulates the Notch signalling pathway in the central nervous system, causing neural stem cell proliferation and differentiation. Additionally, LIPUS can also accelerate tissue repair[ 9 ] and promote the dissipation of inflammation[ 10 ], angiopoiesis[ 11 ], etc.…”
Section: To the Editormentioning
confidence: 99%
“…Tan et al [ 7 ] listed recent studies regarding the action of LIPUS on various neural stem cells and concluded that LIPUS can stimulate stem cells in vitro , promote stem cell proliferation, differentiation, and migration, and maintain stem cell activity. The findings of Wu et al [ 8 ] suggested that LIPUS regulates the Notch signalling pathway in the central nervous system, causing neural stem cell proliferation and differentiation. Additionally, LIPUS can also accelerate tissue repair[ 9 ] and promote the dissipation of inflammation[ 10 ], angiopoiesis[ 11 ], etc.…”
Section: To the Editormentioning
confidence: 99%
“…When dual antiplatelet therapy (DAPT) was applied along with LIPUS, expressions of both Notch1 and Hes1 increased leading to stem cell proliferation and differentiation. 125 Continuous low-intensity ultrasound (cLIUS) increases the expression of SOX9, a transcription factor and main regulator of chondrogenesis. The increase was associated with phosphorylation of ERK1/2, which also caused the nuclear localization of SOX9.…”
Section: Applications Of Ultrasound In Stem Cellsmentioning
confidence: 99%
“…This finding was confirmed by the decreased expression of neural markers like neuron-specific nuclear protein (NeuN) and expression of glial fibrillary acidic protein (GFAP). When dual antiplatelet therapy (DAPT) was applied along with LIPUS, expressions of both Notch1 and Hes1 increased leading to stem cell proliferation and differentiation …”
Section: Applications Of Ultrasound In Stem Cells Engineering and Reg...mentioning
confidence: 99%
“…Spinal cord injury (SCI) is a traumatic disease that causes exercise, sensory, or autonomic dysfunction, thereby directly affecting the quality of life of patients and imposing a heavy financial burden on society and families (1). It is therefore crucial to clarify the pathophysiological processes associated with SCI.…”
Section: Introductionmentioning
confidence: 99%