Low handgrip strength is associated with reduced functional recovery and longer hospital stay in patients with osteoporotic vertebral compression fractures: a prospective cohort study

Nagaoka, Seiko; Yoshimura, Yoshihiro; Eto, Takaki; Kumagi, Mitsukane

doi:10.1007/s41999-020-00446-4

Cited by 8 publications

(5 citation statements)

References 33 publications

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“… 7 ) These factors predict the physical function at discharge in patients with fragile osteoporotic fractures. 16 , 22 , 39 , 40 , 41 ) Hip fractures are often complicated by sarcopenia and tend to result in low muscle mass in the lower limbs. 42 ) In addition, after 10 days of rest in healthy older adults 43 ) and critically ill patients, 44 ) respective losses of muscle mass of 6.3% and 17.7% were observed.…”

Section: Discussionmentioning

confidence: 99%

“…Previous reports have indicated that several factors influence physical function at discharge and outcome destination in patients with fragile osteoporotic fractures. 16 , 22 , 23 , 24 ) Clarifying the significance of phase angle in relation to physical function at discharge and outcome destination may provide useful information for early goal-setting and treatment decision-making. This study aimed to determine whether phase angle is related to discharge destination and physical function at discharge in patients with osteoporotic fragile fractures.…”

Section: Introductionmentioning

confidence: 99%

“…These fractures can lead to adverse events, such as a reduced quality of life in older adults undergoing rehabilitation, death, 11) and depression among communitydwelling women. 12,13) In addition, patients with fragile osteoporotic fractures have been reported to have sarcopenia, 14) reduced physical function, 15) reduced activities of daily living (ADL), 16,17) dysphagia, 18) prolonged hospitalization, 16) reduced quality of life, 19,20) and risk of re-fracture. 21) Despite the potential importance of phase angle, its impact on physical function at discharge and outcome destination has not been studied in patients with fragile osteoporotic fractures.…”

Section: Introductionmentioning

confidence: 99%

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Phase Angle as a Prognostic Predictor for Physical Function in Fragile Osteoporotic Fracture Patients

Ito,

Yoshimura,

Nagano

et al. 2023

PRM

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Objectives: This study aimed to determine whether the phase angle is associated with physical function at discharge and discharge destination in patients with osteoporotic fragile fractures. Methods: This retrospective cohort study included patients with fragile osteoporotic fractures who were admitted to a convalescent rehabilitation ward. The phase angle was calculated using a body composition meter and bioelectrical impedance analysis. The primary outcome was the Functional Independence Measure motor (FIM-motor) score at discharge, and the secondary outcome was discharge to home. Multivariate analysis was used to determine the association between phase angle and FIM-motor scores at discharge and discharge to home. Results: The study included 127 patients (108 women, age 81.2 ± 9.7 years). The median phase angle on admission was 4.1° for men and 3.6° for women. The median FIM-motor score at discharge was 83, with 92 (72.4%) patients discharged home and 35 (27.6%) discharged to a destination other than home. Multiple regression analysis adjusted for confounders revealed a significant independent association between the phase angle and FIM-motor score at discharge (β=0.262, P=0.019). However, no significant association was found between phase angle and discharge destination (odds ratio, 1.350; 95% confidence interval: 0.680–2.670, P=0.391). Conclusions: Phase angle was independently associated with physical function at discharge in patients with fragile osteoporotic fractures. For patients with a reduced phase angle on admission, a multidisciplinary approach, including exercise, nutrition, oral health, and medication, should be implemented to maximize improvement in physical function.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Phase Angle as a Prognostic Predictor for Physical Function in Fragile Osteoporotic Fracture Patients

Ito,

Yoshimura,

Nagano

et al. 2023

PRM

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“…Osteoporotic fractures occur frequently in older adults, with an estimated 9 million cases occurring annually worldwide. 11 ) Furthermore, osteoporotic fractures negatively affect ADL 12 , 13 ) and quality of life. 14 , 15 ) Recently, the phase angle has also been studied in patients with hip fractures and was associated with quality of life 16 ) and the ability to walk and balance.…”

Section: Introductionmentioning

confidence: 99%

Association of Phase Angle Dynamics with Sarcopenia and Activities of Daily Living in Osteoporotic Fracture Patients

Ito,

Yoshimura,

Nagano

et al. 2024

Ann Geriatr Med Res

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Background: This study aimed to determine whether changes in phase angle during rehabilitation are associated with clinical outcomes such as activities of daily living (ADL), skeletal muscle index (SMI), and strength in patients with osteoporotic fractures. Methods:This retrospective observational study included patients with osteoporotic fractures admitted to convalescent rehabilitation wards. Changes in phase angle were defined as the difference between the phase angle values at discharge and on admission. The primary outcome was the Functional Independence Measure Motor (FIM-motor) score at discharge. The secondary outcomes were SMI and handgrip strength at discharge. We used multivariate analysis to adjust for confounding factors and examine the association between changes in the phase angle and outcomes. Results:We analyzed a total of 115 patients (97 women, mean age 81.0 ± 10.0 years), with a median change in phase angle of 0.0° during hospitalization. We observed increased phase angles in 49 patients (43%), with a median increase of 0.2°. Multiple regression analysis showed that changes in phase angle were independently associated with FIM-motor score at discharge (β = 0.238, P = 0.027). Changes in phase angle were not significantly associated with SMI (β = 0.059, P = 0.599) or handgrip strength (β = -0.032, P = 0.773) at discharge. Conclusions:An increased phase angle during rehabilitation was positively associated with 5 ADL improvement in patients with osteoporotic fractures. These findings may help clinicians make informed decisions regarding patient care and treatment strategies for better outcomes.

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“…HGS may be treated as a biomarker, as it can be used to determine overall strength, upper limb function, sarcopenia, frailty syndrome, bone mineral density, fractures, falls, malnutrition, cognitive impairment, depression, sleep problems, diabetes, multimorbidity and quality of life at the same time [4,[7][8][9][10]. Monitoring and sustaining HGS can act as a preventive measure of mortality and the appearance of diseases, functional decline and hospitalization problems [11][12][13][14]. Routine use of HGS can be as a single measurement or as part of several investigations to identify older adults who may present with poor health [4].…”

Section: Introductionmentioning

confidence: 99%

Better Handgrip Strength Is Related to the Lower Prevalence of Pain and Anxiety in Community-Dwelling Older Adults

Sosowska

Guligowska

Sołtysik

et al. 2023

JCM

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Although handgrip strength (HGS) may be treated as a biomarker of many health problems, there is little evidence on the potential role of HGS in the prevention of pain or anxiety in older adults. We investigated the relationship of HGS to the presence of pain and anxiety among community-dwelling older adults. The study was performed in 2038 outpatients, aged 60 to 106 years. The Jamar hand-held hydraulic dynamometer was used to measure HGS. The prevalence of pain and anxiety was assessed with the Euroqol 5D questionnaire. Symptoms of depression were recorded with 15-item Geriatric Depression Scale (GDS). In the multivariate logistic regression model taking into account age, sex, BMI and concomitant diseases, the significant influence of HGS on the presence of pain (odds ratio [OR] = 0.988) in the entire study population and among men (OR = 0.983) was found. HGS was a significant independent predictor for the presence of anxiety in the entire study population (OR = 0.987), in women (OR = 0.985) and in men (OR = 0.988). In the multivariate logistic regression model with GDS included, HGS was still a significant independent predictor of pain in the entire study population (OR = 0.988), of anxiety in the entire study population (OR = 0.987) and of anxiety in women (OR = 0.988). In the fully adjusted model with included GDS, a higher-than-1 kg HGS score was still associated with 1.2% and 1.3% lower probability of the presence of pain and anxiety, respectively. We conclude that low HGS is associated with the presence of pain and anxiety among older adults, independent of age, sex, depression symptoms and concomitant chronic diseases. Future research should assess whether improvement of HGS would alleviate psychological dysfunction in older adults.

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Low handgrip strength is associated with reduced functional recovery and longer hospital stay in patients with osteoporotic vertebral compression fractures: a prospective cohort study

Cited by 8 publications

References 33 publications

Phase Angle as a Prognostic Predictor for Physical Function in Fragile Osteoporotic Fracture Patients

Phase Angle as a Prognostic Predictor for Physical Function in Fragile Osteoporotic Fracture Patients

Association of Phase Angle Dynamics with Sarcopenia and Activities of Daily Living in Osteoporotic Fracture Patients

Better Handgrip Strength Is Related to the Lower Prevalence of Pain and Anxiety in Community-Dwelling Older Adults

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