Low-grade Albuminuria Associated with Subclinical Left Ventricular Diastolic Dysfunction and Left Ventricular Remodeling

Yan, Sunjie; Yao, Fengjuan; Huang, Lingning; Ruan, Qinyun; Shen, Xiaodong; Zhang, S.; Huang, Chunyan

doi:10.1055/s-0035-1550052

Cited by 10 publications

(15 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recently, many researchers have focused on the clinical effects of low-grade albuminuria, which is defined as high level within urinary albumin-to-creatinine ratio (UACR) < 30 mg/g (10)(11)(12)(13)(14)(15)(16). Previous studies have shown an association between a high UACR and various cardiometabolic risk factors (10)(11)(12)(13)(14)(15)(16). In addition, some factors, including various cardiometabolic risk factors, have been shown to predict a high UACR; additional studies investigating new markers of a high UACR are on-going.…”

Section: Introductionmentioning

confidence: 99%

Glycated hemoglobin A1c level is associated with high urinary albumin/creatinine ratio in non-diabetic adult population

et al. 2016

View full text Add to dashboard Cite

Non-DM participants with relatively high HbA1c levels should be closely monitored for UACR, especially if participants do not have MetS. KEY MESSAGES HbA1c level was positively associated with the proportion of participants with a high UACR and logUACR in participants without DM. For participants without MetS, the proportion of participants with a high UACR was greater in the High group than in the other groups and logUACR was greatest in the High group compared to the other groups. For participants with MetS, there were significant associations between HbA1c and the proportion of participants with a high UACR as a categorical variable or logUACR as a continuous variable, but the statistical significance of this finding was weak. No differences were found for proportions of participants with high UACR and logUACR values in the Low, Middle, and High groups.

show abstract

Section: Introductionmentioning

confidence: 99%

Glycated hemoglobin A1c level is associated with high urinary albumin/creatinine ratio in non-diabetic adult population

et al. 2016

View full text Add to dashboard Cite

show abstract

“…Another study carried out with 760 Chinese participants aged from 29 to 76 years, presenting type 2 DM and normoalbuminuria has demonstrated a signi cant association between LGA and increased thickness of the carotid intima-media layer 20 . UACR was associated with subclinical left ventricular diastolic dysfunction and left ventricular remodeling in patients presenting with and without type 2 DM 19 .…”

Section: Discussionmentioning

confidence: 93%

“…The results of this study demonstrate a signi cant association between LGA and 10-year CVD risk in a sample of hypertensive and/or diabetic patients assisted by PHC. Several other studies associate LGA with increased risk of all-cause cardiovascular disease 12,13,[18][19][20][21] , including in apparently healthy individuals presenting no DM or AH 12 . A study carried out with a nationally representative sample of 9,736 adult Koreans associated albuminuria within the normal range with metabolic syndrome 18 .…”

Section: Discussionmentioning

confidence: 99%

Low-Grade Albuminuria and Its Relationship with Cardiovascular Disease Risk in Hypertensive and Diabetic Patients in Primary Health Care

Souza

Silva

Oliveira

et al. 2022

Preprint

View full text Add to dashboard Cite

Objective: To evaluate the presence of LGA and the relationship with the 10-year risk of a cardiovascular event in hypertensive and diabetic patients in Primary Health Care. Study Design: The study design used in the study is a cross-sectional study. Methods: This study was based on the application of questionnaires, anthropometric measurements, and laboratory tests carried out from August 2017 to April 2018. Logistic regression was used to evaluate the odds ratio of the explanatory variables in relation to the highest tercile of LGA. The Framingham risk score was used to assess the 10-year risk of cardiovascular event. The comparison of this score with the LGA terciles was analyzed by using ANOVA. Results: An increase in the 10-year risk of cardiovascular event score was observed with an increasing LGA tercile, and this pattern prevailed after adjusting for confounding variables. Conclusion: An association between LGA and 10-year risk of cardiovascular event was observed in a representative sample of hypertensive and diabetic patients.

show abstract

“…Cardiovascular disease remains the leading cause of death worldwide [1,2]. The prevalence of cardiovascular disease among Chinese population increased steadily, with coronary heart disease (CHD) and stroke accounting for most of deaths [3].…”

Section: Introductionmentioning

confidence: 99%

Relation of Carotid Artery Plaque to Coronary Heart Disease and Stroke in Chinese Patients: Does Hyperglycemia Status Matter?

Zhou

Wang

Zhu

et al. 2017

Exp Clin Endocrinol Diabetes

View full text Add to dashboard Cite

show abstract

Low-grade Albuminuria Associated with Subclinical Left Ventricular Diastolic Dysfunction and Left Ventricular Remodeling

Abstract: UACR was associated with subclinical LV diastolic dysfunction and remodeling in both patients with and without Type 2 diabetes. We conclude that LGA may also be a marker for subclinical cardiovascular damage in Type 2 diabetics.

Cited by 10 publications

References 30 publications

Glycated hemoglobin A1c level is associated with high urinary albumin/creatinine ratio in non-diabetic adult population

Glycated hemoglobin A1c level is associated with high urinary albumin/creatinine ratio in non-diabetic adult population

Low-Grade Albuminuria and Its Relationship with Cardiovascular Disease Risk in Hypertensive and Diabetic Patients in Primary Health Care

Relation of Carotid Artery Plaque to Coronary Heart Disease and Stroke in Chinese Patients: Does Hyperglycemia Status Matter?

Contact Info

Product

Resources

About