Low-flux electron diffraction study on the intercellular lipid organization in the human lip stratum corneum
Junko Kamimoto-Kuroki,
Hiromitsu Nakazawa,
Hiroki Ohnari
et al.
Abstract:We examined the lateral packing structure of intercellular lipids (ICL) in the lip stratum corneum (SC) by low-flux electron diffraction (LFED) to obtain new insights into the causes of high transepidermal water loss (TEWL) and low water retention, which may increase the vulnerability of the lip to chapping. Similar to skin SC-ICLs, we found coexistence of orthorhombic and hexagonal phases in lip SC-ICLs. We also found that electron diffraction (ED) images with no sharp peaks and a relatively small broad peak … Show more
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