Low-Flow, Low-Gradient Severe Aortic Stenosis

Lange, Rüdiger; Vitanova, Keti

doi:10.1016/j.jcin.2021.05.015

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Valvular Heart Disease Treatment Devices1

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2023

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“…Indeed, in the presence of a low transvalvular gradient at baseline or concomitant valvular disease, aortic valve replacement might be considered ineffective from an haemodynamic and prognostic standpoint [ 16 ]. On the other hand, conservative management of these patients has been associated with mortality rates

50% at 3-year follow-up while early post-operative mortality after SAVR reach up to 20% [ 17 , 18 ]. Thus, although current evidence is based only on observational studies, TAVI might be considered the optimal therapeutic option for patients with severe LFLG-AS [ 19 , 20 ].…”

Section: Valvular Heart Disease Treatment Devicesmentioning

confidence: 99%

Update on Percutaneous Treatment for HFrEF: A Great Armamentarium for a Poor Ventricular Function

Sisinni¹,

Casenghi²,

Rubbio³

et al. 2023

Rev. Cardiovasc. Med.

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Pharmacological treatment is the cornerstone therapy of heart failure with reduced ejection fraction (HFrEF). In addition, several percutaneous techniques have been developed to treat symptomatic patients, with specific heart failure (HF) phenotypes (e.g., valvular heart disease) that require non-pharmacological treatment. Given their prognostic relevance, it is imperative to deliver high-level patient care. This review provides a clinical overview on the available data regarding transcatheter devices in the armamentarium of contemporary interventional cardiologists, focusing on the clinical and anatomical selection criteria.

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