Low-field¹H-NMR spectroscopy for compositional analysis of multicomponent polymer systems

Abstract

A low-field, 60 MHz, 1H NMR spectrometer yields quantitatively comparable results to 400 MHz spectrometers for the compositional analysis of multicomponent polymer systems.

Low‐field 1H NMR spectroscopy: Factors impacting signal‐to‐noise ratio and experimental time in the context of mixed microstructure polyisoprenes

“…These findings are consistent with our previous work, where we demonstrated the capability of a 60-MHz spectrometer (Pulsar) to consistently produc compositional data within 2% of the extracted Figure S2 for 400-MHz spectra high-field values for high 1,4-polyisoprene as well as select block copolymers and polymer blends. [18] Even the shortest experiment here,~3 min, is capable of producing quantitatively consistent compositional results which is encouraging for the application of these instruments in quality control applications and reaction monitoring.…”

“…Recently, low-field NMR spectrometers have begun to make a comeback as a viable means to analyze complex systems. [11][12][13][14][15][16][17][18] Earlier versions of NMR spectrometers are what we now identify as low-field NMR spectrometers and differ mainly via their mode of operation and lack of digital analysis equipment. Given the advances in modern technology, current-day low-field NMR spectrometers operate more analogous to high-field spectrometers by pulsing magnetic waves through a sample rather than a singular continuous pulse.…”

“…But when used under the correct operating conditions, they can provide data that is comparable with that of high-field instruments. [16,18,19] Many factors, both instrumental and sample based, impact the spectral data quality obtained from an NMR spectroscopy experiment. [20,21] The instrumental parameters chosen for a given experiment-including spectral width, relaxation delay, the number of data points per scan, and number of scans per experiment-directly affect the resulting spectrum.…”

“…But when used under the correct operating conditions, they can provide data that is comparable with that of high‐field instruments. [ 16,18,19 ] …”

Spectroscopic Methods Used in Implant Material Studies

“…Examples of applied spectroscopic methods include agriculture and food analysis [1,2], environmental Over the last decades, spectroscopic methods have been applied in numerous studies revolving around analytical, biophysical and physical, or organic chemistry and material science. Examples of applied spectroscopic methods include agriculture and food analysis [1,2], environmental problem analysis [3,4], catalyst evaluation [5,6], chemical mapping [7], polymer analysis [8,9], biological surfaces [10], cellular [11][12][13] and tissue analysis [14][15][16][17], biosensing [18,19], and clinical applications [20][21][22].…”