Low Dose Oral Desmopressin for Nocturnal Polyuria in Patients With Benign Prostatic Hyperplasia: A Double-Blind, Placebo Controlled, Randomized Study

Wang, Chung-Jing; Lin, Yung-Yang; Huang, Shi‐Wei; Chang, Chien-Hsing

doi:10.1016/j.juro.2010.08.095

Cited by 58 publications

(64 citation statements)

References 25 publications

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“…nowadays, desmopressin is the most common prescribed medication for nocturia related to nocturnal polyuria. In a randomized double-blind placebo-controlled study, Wang et al [7] evaluated the efficacy of low-dose oral desmopressin in patients with BPH and nocturia associated with nP and found that desmopressin resulted in a significant decrease in nocturnal voiding frequency and the volume of nocturnal urine. However, this study was evaluating desmopressin only effect on nocturia in aging patients with BPH.…”

Section: Discussionmentioning

confidence: 99%

“…Many double-blind placebo-controlled studies were conducted to assess the effect of BPH medical therapies on nocturia associated with BPH and also to assess the effect of desmopressin therapy in BPH patients with nocturnal polyuria (nP) [5,7]. However, treatment for nocturia has been reported to be less satisfactory than treatment of other lUtS and remains one of the most difficult lUts to treat.…”

Section: Introductionmentioning

confidence: 99%

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The impact of adding low-dose oral desmopressin therapy to tamsulosin therapy for treatment of nocturia owing to benign prostatic hyperplasia

et al. 2014

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The impact of adding low-dose oral desmopressin therapy to tamsulosin therapy for treatment of nocturia owing to benign prostatic hyperplasia

et al. 2014

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“…6 Oral desmopressin had effects in patients with BPH especially for nocturnal polyuria. 7 So desmopressin was included for medical treatment modality in our study.…”

Section: Methodsmentioning

confidence: 99%

National-wide data on the treatment of BPH in Korea

Kang

et al. 2011

Prostate Cancer Prostatic Dis

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The healthcare system in Korea provides coverage to all the people who are residing in Korea, so the data of the Korea healthcare system are national-wide and relatively accurate. We obtained the recent 5-year data (2004–2008) on the treatment of BPH from the national health insurance system. We tried to determine the trends or changes of BPH treatments in Korea. Over 3.8 million men visited clinics and were prescribed one or more BPH medications, and more than 44 000 men underwent surgical treatment during 2004–2008. Compared with the year 2004, two times the patients were prescribed BPH medications in 2008. With respect to the surgical treatment, the number of cases was increased 1.6 times in 2006 compared with the previous years. The most commonly used surgical option was TURP before 2006, but laser therapy was carried out as much as TURP in 2006 and in the following years. The relative risk of laser therapy in the 50 s is 1.53 (95% CI is 1.47–1.59). In conclusion, our national-wide data for the Korean BPH patients show that these patients' medical treatment increased during the 5 years from 2004 to 2008. Laser treatment had increased and it might replace TURP in several years.

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“…Wang ve arkadaşları AÜSS ve noktürinin bulunduğu 115 hastalık çalışmalarında, plasebo ile desmopressin tedavisini karşılaştırmışlar ve iki grup arasında anlamlı fark tespit etmişlerdir. [10] Çalışmamızda her iki grupta noktüri açısından bazal değerler ile üçüncü ay kontrol değerleri arasında istatistiksel anlamlı fark tespit edildi.…”

Section: Bulgularunclassified

Desmopressin in the treatment of nocturia with BPH

Koca¹,

Keleş²,

Güneş³

et al. 2012

Turkish Journal of Urology

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Objective: Benign prostate hyperplasia (BPH), whose frequency increases with age, is a disease that negatively affects a patient's quality of life because of its symptoms. Nocturia is one of these unfavorable symptoms. We attempted to demonstrate the effects of desmopressin on the quality of life of these patients. Material and methods:Forty-nine patients between the ages of 50-70 who were referred to our clinic with the complaints of lower urinary tract symptoms and nocturia (≥2/night) were included in the study. These patients were randomized into two groups. Alfuzosin was administered to group 1, and desmopressin with alfuzosin was administered to group 2. All patients were followed at one and three months to assess their symptoms.

show abstract

Low Dose Oral Desmopressin for Nocturnal Polyuria in Patients With Benign Prostatic Hyperplasia: A Double-Blind, Placebo Controlled, Randomized Study

Cited by 58 publications

References 25 publications

The impact of adding low-dose oral desmopressin therapy to tamsulosin therapy for treatment of nocturia owing to benign prostatic hyperplasia

The impact of adding low-dose oral desmopressin therapy to tamsulosin therapy for treatment of nocturia owing to benign prostatic hyperplasia

National-wide data on the treatment of BPH in Korea

Desmopressin in the treatment of nocturia with BPH

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