Low-dose magnesium sulphate in the control of eclamptic fits: a randomized controlled trial

Abstract

The effectiveness of low-dose regimen of magnesium sulphate appeared comparable to the 'standard dose regimen'. Low-dose regimen may guarantee more safety and in an environment (such as ours) where cost is an important determinant of accessibility to qualitative health services, it is certainly attractive. More studies are needed to establish the place of low-dose regimen of magnesium sulphate in the management of eclampsia.

A systematic review of the treatment and management of pre-eclampsia and eclampsia in Nigeria

“…The findings indicated that the shortened postpartum course was as effective as the Pritchard regimen to manage eclampsia. While Chama and Geidam shortened the postpartum maintenance in their study, Abdul et al instead modified the antepartum loading and maintenance doses (Abdul, et al, 2013). During their study, Abdul et al randomized 72 patients into standard dose (n=33) and low dose (n=39) groups.…”

A comparative study of low dose magnesium sulphate therapy with Pritchard’s regime in management of Eclampsia

“…Several studies showed a recurrence rate of 4-6% with low dose magnesium sulphate therapy. [9][10][11] The recurrence rate with standard protocol reported in collaborative eclamptic trial, the largest multicentre randomized controlled trial ranged between 5.7% and 13.2%. Suman et al and Begum R, of Dhaka have concluded that the low dose magnesium sulphate therapy is as effective as standard Pritchard's regime in the Asian group.…”

A comparative study of low dose magnesium sulphate therapy with standard pritchard's regime in the management of eclampsia

“…Several studies showed a recurrence rate of 4-6% with low dose magnesium sulphate therapy. [10][11][12] The recurrence rate with standard protocol reported in collaborative eclamptic trial, the largest multicentre randomized controlled trial ranged between 5.7% and 13.2%. The two Asian studies one by Suman P et al and another by R. Begum of Dhaka have concluded that the low dose magnesium sulfate therapy is as effective as standard Pritchard's regime in the Asian Group.…”