Low-dose GBCA administration for brain tumour dynamic contrast enhanced MRI: a feasibility study
Daniel Lewis,
Ka-Loh Li,
Mueez Waqar
et al.
Abstract:A key limitation of current dynamic contrast enhanced (DCE) MRI techniques is the requirement for full-dose gadolinium-based contrast agent (GBCA) administration. The purpose of this feasibility study was to develop and assess a new low GBCA dose protocol for deriving high-spatial resolution kinetic parameters from brain DCE-MRI. Nineteen patients with intracranial skull base tumours were prospectively imaged at 1.5 T using a single-injection, fixed-volume low GBCA dose, dual temporal resolution interleaved DC… Show more
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