1982
DOI: 10.1213/00000539-198208000-00011
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Low-Dose Fentanyl Blunts Circulatory Responses to Tracheal Intubation

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Cited by 107 publications
(48 citation statements)
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“…In a study of 950 patients, Hung et al 14 observed that the lighted stylet had a shorter time of intubation, a result different from ours. However, Ellis et al 15 reported similar results to the present study, which showed no statistical significant difference between groups.…”
Section: Discussioncontrasting
confidence: 88%
“…In a study of 950 patients, Hung et al 14 observed that the lighted stylet had a shorter time of intubation, a result different from ours. However, Ellis et al 15 reported similar results to the present study, which showed no statistical significant difference between groups.…”
Section: Discussioncontrasting
confidence: 88%
“…The practice of administering an opiate analgesic prior to airway instrumentation is well established, and fentanyl has been shown to moderate independently the haemodynamic response to tracheal intubation. 15,16 However, the dose of fentanyl which is necessary to abolish the pressor response completely may be associated with undesirable side-effects, including delayed respiratory depression and, occasionally, hypotension following administration of thiopentone. The multicentre study showed that the combination of esmolol 100 mg with low-dose narcotic (fentanyl 2-3 ixg.kg -1 equivalent) resulted in effective control of both heart rate and blood pressure in response to tracheal intubation.…”
Section: Discussionmentioning
confidence: 99%
“…A dose of 5-6 I~g" kg -I of a narcotic such as fentanyl, when given prior to induction with thiopentone, is effective in preventing hypertension and tachycardia secondary to intubation. 3,4 However, fentanyl should be administered approximately five minutes prior to induction, in order to allow sufficient time to reach peak analgesic effect before the stimulus of intubation. 8 Furthermore, this technique may be in appropriate for surgical procedures of short duration, due to relatively prolonged respiratory depression with this dose of fentanyl.…”
Section: Discussionmentioning
confidence: 99%