Low-dose CT of the lung: potential value of iterative reconstructions

Baumueller, Stephan; Winklehner, Anna; Karlo, Christoph; Goetti, Robert; Flohr, Thomas; Russi, Erich W.; Frauenfelder, Thomas; Alkadhi, Hatem

doi:10.1007/s00330-012-2524-0

Cited by 135 publications

(106 citation statements)

References 29 publications

(30 reference statements)

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“…The newest generation of CTs, in combination with iterative reconstruction techniques [14], allow for ultralow-dose CT acquisitions with effective doses similar to the dose of the topogram, and thus, not more than the dose with conventional thoracic radiography in two projections, which is 0.05-0.24 mSv [15]. These ultralow-dose CT acquisitions allow a high sensitivity and diagnostic confidence for the detection of pulmonary nodules [16].…”

Section: Introductionmentioning

confidence: 99%

Performance of ultralow-dose CT with iterative reconstruction in lung cancer screening: limiting radiation exposure to the equivalent of conventional chest X-ray imaging

et al. 2016

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Section: Introductionmentioning

confidence: 99%

Performance of ultralow-dose CT with iterative reconstruction in lung cancer screening: limiting radiation exposure to the equivalent of conventional chest X-ray imaging

et al. 2016

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“…6,7,15 This study demonstrates that half-dose CT images reconstructed using SAFIRE were superior to standard-dose images in regards to subjective im- This study found that the sharpness of the and another group selected S2 and S3, as the optimal strength levels for low-dose lung CT. 16,17,19 These differences may be influenced by body mass index (BMI), given that image noise is higher in patients with higher BMIs. 25 The mean BMI in previous studies is slightly higher than in our study.…”

Section: Discussionmentioning

confidence: 99%

Performance of Half-dose Chest Computed Tomography in Lung Malignancy Using an Iterative Reconstruction Technique

Kang

Park

et al. 2017

KMJ

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Objectives:The purpose of this study was to evaluate the performance of half-dose chest CT using an iterative reconstruction technique in patients with lung malignancies. Methods: The Dual-source CT scans were obtained and half-dose datasets were reconstructed with 5 different strengths in 38 adults with lung malignancies. Two radiologists graded subjective image quality; noise, contrast and sharpness at the central/peripheral lung, mediastinum and chest wall of the reconstructed half-dose images, compared with those of standard-dose images, using a three-point scale. A lesion assessment; lesion conspicuity and diagnostic confidence, was also performed. The quantitative image noises; contrast-to-noise ratio (CNR) and signal-to-noise ratio (SNR) were measured and compared with those of standard-dose images. Results: The subjective image noise in the half-dose images was less than that of the standard-dose images. The contrast in strengths 2 to 5 was superior, the sharpness of the lung parenchyma in strengths 3 to 5 was inferior, and the CNR/SNR in all strengths were higher than those of standard-dose images (P < 0.05). The improvement of subjective image noise and contrast, the decrease in sharpness, were correlated with strength level (P < 0.05). The lesion conspicuity in half-dose images of strengths 4 and 5 was decreased. The diagnostic confidence of the half-dose images of all strengths was comparable to that of the standard-dose images (P < 0.05). Conclusions: Half-dose chest CT images using an iterative reconstruction technique show decreased image noise, increased contrast, and diagnostic confidence comparable to standard-dose images. Images reconstructed with strength 2 and 3 appear to be the optimal choice in clinical practice.

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“…In the literature, there is a wide variation of dose-reduction results by using SAFIRE, [15][16][17][18][19][20][21] which makes it difficult to compare results. Differences might be partially explained by the inconsistency FIG 1. Boxplot diagrams.…”

Section: Discussionmentioning

confidence: 99%

“…Sinogram-Affirmed Iterative Reconstruction (SAFIRE) is a raw data and image domain-based 15 noise-modeling technique with 5 user-selectable strength levels. Previous work established the feasibility of SAFIRE for the study of body regions [15][16][17][18][19][20] and more recently in head CT 21 applications.…”

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confidence: 99%

Repeated Head CT in the Neurosurgical Intensive Care Unit: Feasibility of Sinogram-Affirmed Iterative Reconstruction–Based Ultra-Low-Dose CT for Surveillance

Corcuera‐Solano

Doshi

Noor

et al. 2014

AJNR Am J Neuroradiol

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BACKGROUND AND PURPOSE:Patients in the neurosurgical intensive care unit undergo multiple head CT scans, resulting in high cumulative radiation exposures. Our aim was to assess the acceptability of a dedicated, special-purpose sinogram-affirmed iterative reconstruction-based ultra-low-dose CT protocol for neurosurgical intensive care unit surveillance head CT examinations, comparing image quality with studies performed with our standard-of-care sinogram-affirmed iterative reconstruction low-dose CT and legacy filtered back-projection standard-dose CT protocols.

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Low-dose CT of the lung: potential value of iterative reconstructions

Abstract: Low-dose computed tomography is an important thoracic investigation tool. Radiation dose can be less than 1 mSv with iterative reconstructions. Iterative reconstructions render more low-dose lung CTs diagnostic compared to conventional reconstructions.

Cited by 135 publications

References 29 publications

Performance of ultralow-dose CT with iterative reconstruction in lung cancer screening: limiting radiation exposure to the equivalent of conventional chest X-ray imaging

Performance of ultralow-dose CT with iterative reconstruction in lung cancer screening: limiting radiation exposure to the equivalent of conventional chest X-ray imaging

Performance of Half-dose Chest Computed Tomography in Lung Malignancy Using an Iterative Reconstruction Technique

Repeated Head CT in the Neurosurgical Intensive Care Unit: Feasibility of Sinogram-Affirmed Iterative Reconstruction–Based Ultra-Low-Dose CT for Surveillance

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