Low‐Dose Botulinum Toxin Type A for the Treatment of Refractory Piriformis Syndrome

Yoon, Se Jin; Ho, Jin Young; Kang, Ho Yeong; Lee, Sang Ho; Kim, Kyung Im; Shin, Wonjae; Oh, Jung Mi

doi:10.1592/phco.27.5.657

Cited by 66 publications

(53 citation statements)

References 34 publications

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“…In fact, even in a situation of normal relationship between the sciatic nerve and the piriformis muscle, any condition affecting the muscle (e.g., inflammation or trauma) could indirectly affect the nerve. This idea seems to be particularly supported by the good pain relief results achieved when low doses of botulinum toxin are injected into the piriformis muscle of patients with typical signs and symptoms of the piriformis syndrome 12 .…”

Section: Discussionmentioning

confidence: 98%

Variações anatômicas do nervo ciático em um grupo de cadáveres brasileiros

Brooks¹,

Silva²,

Soares³

et al. 2011

Rev. dor

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Section: Discussionmentioning

confidence: 98%

Variações anatômicas do nervo ciático em um grupo de cadáveres brasileiros

Brooks¹,

Silva²,

Soares³

et al. 2011

Rev. dor

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“…Botulinum toxin injections in PS 14,21,29,35,48,84,87,90,[102][103][104] Botulinum toxin type A is one of seven immunologically distinct serotypes (A-G) of neurotoxin produced by Clostridium botulinum. Botulinum toxin type A can be administered with fluoroscopic, electromyelographic, CT, or MRI guidance.…”

Section: Injection Solutionmentioning

confidence: 99%

“…The recommended dose of botulinum toxin type A in PS is usually 100-200 units diluted in small volumes (1-1.5 mL) of normal saline. 2,14,21,35,102 In summary, the indications, techniques, dosages, and monitoring vary significantly. This variability limits any comparison of studies and treatment groups.…”

Section: Injection Solutionmentioning

confidence: 99%

Brief review: Piriformis syndrome: etiology, diagnosis, and management

Jankovic¹,

Peng

Zundert

2013

Can J Anesth/J Can Anesth

131

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In this narrative review, we aim to provide the pathophysiology and diagnostic criteria of the piriformis syndrome (PS), an underdiagnosed cause of buttock and leg pain that can be difficult to treat. Based on existing evidence, frequencies of clinical features are estimated in patients reported to have PS. In view of the increasing popularity of ultrasound for intervention, the ultrasound-guided technique in the treatment of PS is described in detail. A literature search of the MEDLINEA (R) database was performed from January 1980 to December 2012 using the search terms e.g., " piriformis injection", " ultrasound guided piriformis injection", " botulinum toxin", "pain management", and different structures relevant in this review. There was no restriction on language. A review of the medical literature pertaining to PS revealed that the existence of this entity remains controversial. There is no definitive proof of its existence despite reported series with large numbers of patients. Piriformis syndrome continues to be a controversial diagnosis for sciatic pain. Electrophysiological testing and nerve blocks play important roles when the diagnosis is uncertain. Injection of local anesthetics, steroids, and botulinum toxin into the piriformis muscle can serve both diagnostic and therapeutic purposes. An ultrasound-guided injection technique offers improved accuracy in locating the piriformis muscle. Optimizing the therapeutic approach requires an interdisciplinary evaluation of treatment

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“…Some recent data has advocated the use of botulinum toxin (onabotulinumtoxin A) in patients with diagnosed piriformis syndrome. In 2007, Yoon et al [39] injected 20 patients with 50 units of botulinum toxin (onabotulinumtoxin A) using CT guidance. This group was compared to nine control patients receiving corticosteroid.…”

Section: Piriformis Syndromementioning

confidence: 99%

Image-Guided Injections of the Hip

Singh¹

2014

J Nov Physiother Phys Rehabil

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The authors present a technique paper on the utilization of both ultrasound and fluoroscopy guidance for injections about the hip joint. This review draws from specialists including physiatry, family medicine and orthopaedic surgery. We hope the editors and reviewers find this document beneficial to the readership, especially those practicing musculoskeletal medicine and may use this information when performing hip injections.

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Low‐Dose Botulinum Toxin Type A for the Treatment of Refractory Piriformis Syndrome

Abstract: A low dose of botulinum toxin type A relieved pain and improved quality of life in patients with refractory piriformis syndrome.

Cited by 66 publications

References 34 publications

Variações anatômicas do nervo ciático em um grupo de cadáveres brasileiros

Variações anatômicas do nervo ciático em um grupo de cadáveres brasileiros

Brief review: Piriformis syndrome: etiology, diagnosis, and management

Image-Guided Injections of the Hip

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