Low-dose aspirin does not improve ovarian stimulation, endometrial response, or pregnancy rates for in vitro fertilization

Tassa, J. Morís-de la; Marshburn, Paul B.; Papadakis, Margaret A; Loeb, T. A.; Matthews, Michelle L.; Hurst, Bradley S.

doi:10.1016/s0015-0282(02)04095-5

Fertility and Sterility

2002

DOI: 10.1016/s0015-0282(02)04095-5

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Low-dose aspirin does not improve ovarian stimulation, endometrial response, or pregnancy rates for in vitro fertilization

J. Morís-de la Tassa¹,

Paul B. Marshburn

Margaret A Papadakis

et al.

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Cited by 2 publications

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References 25 publications

(6 reference statements)

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“…Aspirin has been studied in the context of in vitro fertilization (IVF), specifically to investigate whether any change occurs in endometrial thickness, ovarian blood flow, or the quality of oocytes (10)(11)(12)(13)(14)(15)(16)(17)(18)(19). The results of these studies are mixed.…”

mentioning

confidence: 99%

Low-dose aspirin use does not improve in vitro fertilization outcomes in poor responders

Frattarelli

McWilliams

Hill

et al. 2008

Fertility and Sterility

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mentioning

confidence: 99%

Low-dose aspirin use does not improve in vitro fertilization outcomes in poor responders

Frattarelli

McWilliams

Hill

et al. 2008

Fertility and Sterility

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Drug intervention in early pregnancy after assisted reproductive technology

Ozturk¹,

Sarıdoğan²,

Jauniaux³

2004

Reproductive BioMedicine Online

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Implantation in humans is a complex, closely regulated, highly selective and relatively poorly understood process. Humans have the highest rate of miscarriage in mammals and various pharmacological manipulations have been used to minimize pregnancy losses in both spontaneous pregnancies and pregnancies resulting from assisted reproduction technology. The widespread application of protocols using numerous drugs in assisted reproduction treatment has led to an increasing number of pregnancies exposed to these drugs. The vast majority of these protocols have been based on data from a few observational and often retrospective clinical studies. This paper reviews the recent literature on drug interventions in early pregnancy after assisted reproduction treatment. It is concluded that there are still numerous issues about the safety of most drugs for both the women and their fetus. In many cases, the benefits are theoretical and the possible long-term side-effects are untested. There is an urgent need for more epidemiological studies and randomized controlled trials to explore the use, efficacy and side-effects of both old and new drugs in early pregnancy after assisted reproduction treatment.

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Low-dose aspirin does not improve ovarian stimulation, endometrial response, or pregnancy rates for in vitro fertilization

Cited by 2 publications

References 25 publications

Low-dose aspirin use does not improve in vitro fertilization outcomes in poor responders

Low-dose aspirin use does not improve in vitro fertilization outcomes in poor responders

Drug intervention in early pregnancy after assisted reproductive technology

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