Low Diagnostic Performance of Thick Blood Smears of 50 µL in Comparison with Blood Direct Examination of 10 µL and Leukoconcentration Techniques among Loiasis-Suspected Patients with Low Microfilaremia in Gabon, Central Africa, using the STARD-BCLM Guidelines
Noé Patrick M’Bondoukwé,
Matthieu Owono-Medang,
Marie Noëlle Moussavou-Boussougou
et al.
Abstract:Background
The aim of the study was to determine performance indicators of the Thick Blood Smear of 50 µL (TBS-50), following Standards for the Reporting of Diagnostic Accuracy Studies-Bayesian Latent Class Analysis (STARD-BLCA) guidelines. TBS-50 was compared to two common parasitological techniques – the blood direct examination of 10 µL and the leukoconcentration of 5 mL.
Methods
The study population was recruited among the patients of the Department of Parasitology-Mycology-Tropical Medicine of the Facu… Show more
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