Low-Cost Microcomputer-Based Densitometer

Abstract

We have constructed low-cost equipment for the measurement of the optical density of x-ray films. This equipment is based on a video system connected via an analog to digital converter to an Apple microcom puter. The optical density of an x-ray film can thus be

Local Cerebral Blood Flow in Rats with Congenital Hydrocephalus

“…Coverslips were mounted on cards and, after at least 3 days were exposed to x-ray film in a cassette for 2 weeks together with ['4C]methylmethacrylate standards (micro scales, Amersham). Tissue 14C concentration was determined in ten brain regions with a microcomputer based densitometer (Richards et al, 1985 ). Between five and 10 readings were made for each region and the mean LCBF calculated using the operational equation of Rei vich et al (1 969).…”

Proceedings of the Physiological Society, 7‐8 January 1988, Southampton Meeting: Demonstrations

“…Much of the equipment used for CBF measurement has been designed and built in Southampton. We will demonstrate our cerebral blood flow trolley used in patient studies using '33Xe (Lovick et al 1982), hydrogen clearance amplifiers and low-cost densitometer used' in quantitative autoradiography (Richards et al 1985).…”

Proceedings of the Physiological Society, 19‐20 June 1987, Glasgow Meeting: Communications

“…However, when measuring LCBF or LCGU in the cerebral cortex, it is normal to take readings at layer IV, where the autoradiograms are darker. Our densitometer (Richards, Lovick & Pickard, 1985) has the facility to scan across the cerebral cortex. LCGU and LCBF were reduced in all animals towards both the periventricular and outer surfaces of the cortex (visual, auditory, parietal, sensory-motor and frontal regions).…”