Low-cost and green dispersive solid phase extraction of hydrophilic compounds using titanium dioxide nanoparticles

Siderophore purification with titanium dioxide nanoparticle solid phase extraction

“…20 E4 (NaH 2 PO 4 100 mM, pH 8) also did not elute high proportions of DFOB (16.9 ± 0.4%), despite the well documented ability of inorganic phosphate to compete for TiO 2 binding sites. 20,39,40 The same was observed for E5 (3.5 ± 0.4%), that contained 25 times less phosphate at a higher pH. Only the combination of high pH and a high concentration of phosphate resulted in quantitative DFOB recoveries (91.9 ± 3.3%) from TiO 2 (E7, NaH 2 PO 4 100 mM, pH 12.6).…”

“…18,19 Dziomba et al showed that this adsorption capacity could also be used for extraction of smaller hydrophilic phosphocompounds, like thiamine phosphates. 20 Catecholates, hydroxamates and mixed ligands also adsorb on TiO 2 surfaces, [21][22][23] suggesting that TiO 2 may be suitable as solid phase for siderophores. Elution of these compound classes from TiO 2 , however, was not reported.…”