Low contrast non-color vision in patients with multiple sclerosis

Abstract

The results demonstrated low-contrast vision dysfunction while high-contrast vision remained intact. The level of low-contrast vision in MS patients differed significantly from that in the controls. The higher severity of visual disturbances was identified during high illumination. The direct correlation between the degree of low-contrast vision dysfunction and the level of disability on EDSS was found.

Metabolic changes in normal appearing white matter in multiple sclerosis patients using multivoxel magnetic resonance spectroscopy imaging

“…Here, the significant decrease in the NAA/Cr ratio in the frontal NAWM may in part account for the phenomenon of cognitive deficits that occurs in most MS patients, and this has been demonstrated by previous studies. [ 36 – 39 ] For example, a global memory disorder involving indices for short-term memory, long-term memory, and working memory was found in MS patients in Staffen et al's study, [ 40 ] and deficits in decision-making under risk conditions, which might be related to deficits in processing speed or visuospatial learning, were found in MS patients in a study by Rovaris M and colleagues [ 41 ] Regarding NAA/Cr abnormalities in the parietal-occipital NAWM, Kotov et al's [ 42 ] work showed that they may be associated with vision impairment caused by MS.…”