Abstract:Recent data implicate the secreted peptide adropin in the physiology of aging. In humans, adropin is highly expressed in brain tissues, and correlates positively with transcriptomic signatures of mitochondrial and synaptic functions. Adropin treatment improves performance of old mice in cognitive tests requiring learning and memory. While detected in the circulation of humans, no studies have investigated relationships between adropin, cognitive decline and aging. Here we compared serum adropin concentrations … Show more
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