2020
DOI: 10.3390/nu13010110
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Low-Carbohydrate High-Fat Diet and Exercise: Effect of a 10-Week Intervention on Body Composition and CVD Risk Factors in Overweight and Obese Women—A Randomized Controlled Trial

Abstract: We assessed the effect of weight-loss induced with a low-carbohydrate-high-fat diet with and without exercise, on body-composition, cardiorespiratory fitness and cardiovascular risk factors. A total of 57 overweight and obese women (age 40 ± 3.5 years, body mass index 31.1 ± 2.6 kg∙m−2) completed a 10-week intervention using a low-carbohydrate-high-fat diet, with or without interval exercise. An equal deficit of 700 kcal∙day−1 was prescribed, restricting diet only, or moderately restricting diet and adding exe… Show more

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Cited by 15 publications
(20 citation statements)
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“…In other related studies, there is evidence that the efficacy of KD is tied to sex [ 36 ]. Though TG was not expected to decrease in women taking oral contraceptives [ 37 , 38 ], its drop can be attributed to the fact that, in parallel to this group, a decrease in body weight was also observed [ 39 ]. This was manifested in BMI, a reduction in appetite and lipogenesis, and an increase in lipolysis, the energy cost of gluconeogenesis, and the thermal effect of proteins [ 40 ].…”
Section: Discussionmentioning
confidence: 99%
“…In other related studies, there is evidence that the efficacy of KD is tied to sex [ 36 ]. Though TG was not expected to decrease in women taking oral contraceptives [ 37 , 38 ], its drop can be attributed to the fact that, in parallel to this group, a decrease in body weight was also observed [ 39 ]. This was manifested in BMI, a reduction in appetite and lipogenesis, and an increase in lipolysis, the energy cost of gluconeogenesis, and the thermal effect of proteins [ 40 ].…”
Section: Discussionmentioning
confidence: 99%
“…The diet programme consisted of about 10%–20% protein, 45%–60% carbohydrates and 20%–35% fat, and was continued for 10 weeks to achieve the goal of clinically significant weight loss (approximately 5%–10%). 12 , 13 …”
Section: Methodsmentioning
confidence: 99%
“…In obese individuals, a previous systematic review has shown that mild low carbohydrate diet (40% of total energy) was not associated with decrease in fat mass [ 36 ]. Recently, a randomized control trial with 57 women (age 40 ± 3.5 years, BMI 31.1 ± 2.6 kg∙m −2 ) yielded similar results, with low-carbohydrate-high-fat diet having no superior effect on FM in comparison to a normal diet [ 37 ]. However, some carbohydrate sources can be beneficial, while others are not, depending at least in part on their fiber content [ 38 ].…”
Section: Dietary Intake and Clinical Endpoints In Menopausal Womenmentioning
confidence: 97%