Low back pain: Epidemiology of consultations

Jöud, Anna; Petersson, Ingemar F; Englund, Martin

doi:10.1002/acr.21642

Cited by 81 publications

(85 citation statements)

References 14 publications

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“…Based on previous work in Sweden, 10 11 14 22 together with discussions within the research team, ICD-10 codes for the morbidities were identified. Low back pain included codes with the terms ‘backache’ and ‘back pain’ with no region (lower or upper) stated, as it is presumed the majority of these will be related to low back pain.…”

Section: Methodsmentioning

confidence: 99%

“…Diagnostic codes from private care are not automatically transferred to the SHCR. The proportion of contacts with private primary care doctors is approximately 30% of all primary care doctor visits and, therefore, the denominator for the Sweden database was reduced by 30% 14. This correction was not designed to address the separate issue of direct access to physiotherapy for low back pain in the Swedish healthcare system, which remained a potential source of bias in the two-country comparison.…”

Section: Methodsmentioning

confidence: 99%

“…Since private specialised care is less common than for primary care, the denominator for Sweden for all healthcare was reduced by 15%. The derivation and empirical justification of these adjustments have been presented in earlier papers 10 11 14…”

Section: Methodsmentioning

confidence: 99%

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International comparisons of the consultation prevalence of musculoskeletal conditions using population-based healthcare data from England and Sweden

et al. 2013

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ObjectivesTo assess the consultation prevalence of musculoskeletal (MSK) conditions as presented in different healthcare systems, and to determine the feasibility of comparing prevalence figures between nations.MethodsThe settings were an English regional database (Consultations in Primary Care Archive (CiPCA)) and the Swedish Skåne County Health Care Register. Case definitions, data extraction and analysis procedures were harmonised. The number of people consulting per 10 000 registered population in primary care, and in primary or secondary care, in the year 2010 (annual consultation prevalence) were determined for doctor-diagnosed osteoarthritis (OA), rheumatoid arthritis (RA), low back pain, and spondyloarthritis including psoriatic arthritis and ankylosing spondylitis (AS). Seven-year period consultation prevalences were also determined.ResultsCombining primary and secondary care, annual consultation prevalences of any MSK condition (2143 vs 1610/10 000) and low back pain (587 vs 294/10 000) were higher in England than in Sweden, but higher for RA, spondyloarthritis and psoriatic arthritis in Sweden. Annual primary care prevalence figures for OA (176 vs 196/10 000), RA (25 vs 26/10 000), spondyloarthritis (both 8/10 000) and psoriatic arthritis (5 vs 3/10 000) were similar between England and Sweden. AS was rarely recorded in Swedish primary care. These patterns were also observed for 7-year period consultation prevalences.ConclusionsA rigorous methodological approach allowed feasible comparison of MSK consultation prevalence between England and Sweden. Differences in prevalence of inflammatory and unspecific pain conditions may be partially explained by known variations in healthcare systems and recording practice. Routine healthcare data offers potential for investigating variations in occurrence and outcome of MSK conditions between nations.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

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International comparisons of the consultation prevalence of musculoskeletal conditions using population-based healthcare data from England and Sweden

et al. 2013

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“…Many people worldwide suffer from low back pain (LBP), which causes serious socioeconomic problems [1-2]. Many studies have confirmed that intervertebral disc degeneration (IDD) is the leading cause of low back pain.…”

Section: Introductionmentioning

confidence: 99%

Hemeoxygenase-1 Suppresses IL-1β-Induced Apoptosis Through the NF-κB Pathway in Human Degenerative Nucleus Pulposus Cells

Zhu

Jiang

Cheng

et al. 2018

Cell Physiol Biochem

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Background/Aims: Nucleus pulposus cell (NPC) apoptosis is the main factor in intervertebral disc degeneration (IDD); thus, inhibiting the excessive apoptosis of nucleus pulposus cells may be a potential way to alleviate IDD. The effect of Hemeoxygenase-1 (HO-1) on human NPC apoptosis has never been reported. Our study aimed to investigate the effect and mechanism of HO-1 on apoptosis in human degenerative NPCs. Methods: Nucleus pulposus tissues were collected from patients with lumbar vertebral fracture (LVF) and IDD. The expression of HO-1 and P65 in intervertebral discs was determined using immunohistochemistry and western blot analysis. Apoptosis of human nucleus pulposus cells was quantified by flow cytometric analysis. A recombinant lentiviral vector overexpressing HO-1 and HO-1-siRNA was used to promote or silence the expression of HO-1 in nucleus pulposus cells. The NF-κB inhibitor PDTC was used to inhibit the NF-κB pathway. Results: Our study demonstrated that compared with normal samples, IDD samples showed down-regulation of HO-1 expression and up-regulation of P65 expression. Overexpression of HO-1 inhibited the increase in nucleus pulposus cell apoptosis after IL-1β treatment and simultaneously inhibited the expression of p-P65. Furthermore, after treatment with PDTC, the number of apoptotic cells was significantly decreased with or without overexpression of HO-1. Conclusion: HO-1 might play a significant role in IDD, and HO-1 protected degenerative human NPCs against apoptosis induced by IL-1β through the NF-κB pathway. These findings would aid in the development of novel therapeutic approaches for IDD treatment.

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“…According to some previous studies shoulder has been reported as the third most common site of musculoskeletal pain after low back pain [1] and knee pain [2]. Shoulder pain (SP) is recognized as a common complaint globally [2,3] and it is reported to be a frequent reason for consultation in clinical practice [4,5].…”

Section: Introductionmentioning

confidence: 99%

Pattern and Physiotherapy Management of Shoulder Pain A 5-Year Retrospective Audit of a Nigerian Tertiary Hospital

Ayanniyi¹,

Dosumu²,

Mbada³

2016

Med-Science

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Low back pain: Epidemiology of consultations

Cited by 81 publications

References 14 publications

International comparisons of the consultation prevalence of musculoskeletal conditions using population-based healthcare data from England and Sweden

International comparisons of the consultation prevalence of musculoskeletal conditions using population-based healthcare data from England and Sweden

Hemeoxygenase-1 Suppresses IL-1β-Induced Apoptosis Through the NF-κB Pathway in Human Degenerative Nucleus Pulposus Cells

Pattern and Physiotherapy Management of Shoulder Pain A 5-Year Retrospective Audit of a Nigerian Tertiary Hospital

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