“…Semiconductor and metal-clad optical waveguides allow for the modulation of the properties of propagating light due to coupling between the lossless modes of the dielectric waveguide and the lossy optical modes supported by the thin cladding layer [ 18 , 19 , 20 , 21 ]. This coupling depends on the thickness and refractive index of the cladding layer, as well as on the refractive index of the surrounding medium, which makes this type of guided-wave structures suitable for refractometric (bio)sensing [ 22 , 23 , 24 , 25 , 26 , 27 , 28 ]. Compared to metal-clad configurations, the use of a semiconductor layer cladding allows for the use of both transverse electric (TE) (the electric field has no component in the direction of propagation) and transverse magnetic (TM) (the magnetic field has no component in the direction of propagation) polarization modes [ 18 , 19 ] and offers the possibility of obtaining higher refractive index sensitivities [ 25 ].…”