“…In parallel, several studies have found an association between specific cytogenetic profiles identified by interphase fluorescence in situ hybridization (iFISH) and/or high-density single-nucleotide polymorphism (SNP) arrays and prognostic features of PDAC [13,[38][39][40][41]. Thus, alterations of chromosomes 4, 7, 9q34 17q, and 20, in the absence of abnormalities involving chromosome 18q, including specific (numerical) alterations of chromosomes 4, 7, and 9q34 [11] and gains/amplification of chromosome 8q24, 17q, and 20q, have all been associated with more extended and disseminated disease at diagnosis and/or a poorer patient outcome [8,11,13,[41][42][43].…”