“…These are proteins involved in inflammation, oxidative stress, apoptosis, cell survival, endoplasmic reticulum stress response, aging, and other cell processes ( Figure 1 ). These novel biomarkers of DRN include galectin-3 [ 18 , 34 – 36 ] serine racemase (SRR) and its product, D-serine [ 37 – 40 ], REDD1 [ 41 , 42 ], hyperphosphorylated tau [ 43 ], α A-crystallin [ 44 ], SIRT6 [ 45 ], thioredoxin [ 46 , 47 ], CNT [ 48 ], and XBP1 [ 49 ]. They might become promising targets for timely diagnosis and treatment of DRN in the future.…”