Loss of vision caused by expansion of intraocular perfluoropropane (C3F8) gas during nitrous oxide anesthesia

Hart, Richard H.; Vote, Brendan J.; Borthwick, James H.; McGeorge, Archibald J.; Worsley, David

doi:10.1016/s0002-9394(02)01654-9

Cited by 37 publications

(18 citation statements)

References 7 publications

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“…[6][7][8][9] Sulfurhexafluoride (SF6) and perfluoropropane (C3F8) are the most commonly used gases. Bubbles can remain in the eye up to 70 days depending on the concentration, volume and type of the gas.…”

Section: Discussionmentioning

confidence: 99%

“…Hart et al reported their three CRAO cases similar with Lee's case, related with NO anesthesia, within few months after PPV and C3F8 injection. 7 In order to prevent these complications, the anesthesiologist must be aware of the presence of gas within the eye. High altitude is also a main risk factor for the cases with intraocular gas tamponade.…”

Section: Discussionmentioning

confidence: 99%

“…1,2 It may also occur after ocular and extra ocular surgeries related with anesthesia and long-acting intraocular gases. [3][4][5][6][7][8][9] Herein, we report a case of acute CRAO which developed two weeks after combined pars plana vitrectomylensectomy and intraocular silicone oil (SO) tamponade and, to the best of our knowledge, a case like ours has not been reported previously.…”

Section: Introductionmentioning

confidence: 99%

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Göz içi Silikon Yağı Tamponatı ile İlişkili Akut Santral Retinal Arter Tıkanıklığı

...

2012

Tjo

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Sum maryMany systemic and ocular factors may cause acute central retinal artery occlusion (CRAO). Herein, we aimed to describe a case of CRAO due to intraocular silicone oil (SO) tamponade. To the best of our knowledge, a case like our has not been reported previously. A 58-yearold male patient had undergone combined pars plana vitrectomy-lensectomy and intraocular SO for lens luxation and vitreus hemorrhage associated with a blunt ocular trauma in his right eye. Two weeks after the surgery, he presented with acute vision loss in the same eye. He was diagnosed with acute CRAO and it should be related with mechanical press or raised intraocular pressure (IOP) associated with SO. He was treated by partial removal of SO immediately. In spite of the regression of retina edema, his visual acuity did not improve due to optic atrophy. SO may cause CRAO due to raised IOP and/or its mechanical pressure and this complication must be kept in mind. ÖzetPek çok sistemik ve oküler hastalık, akut santral retinal arter tıkanıklığına (SRAT) sebep olmaktadır. Çalışmamızda, daha önce benzer bir hastanın yayınlanmadığını düşündüğümüz, göz içi silikon yağı tamponatı ile ilişkili olarak gelişen SRAT olgusunu sunmayı amaçladık. 58 yaşındaki erkek olgunun sağ gözüne, künt göz travması sonrasında pars plana vitrektomi, lensektomi ve göz içine silikon yağı enjeksiyonu yapıldı. Cerrahiden iki hafta sonra aynı gözde akut görme kaybı gelişti. Olgumuzda, silikon yağının doğrudan basısı ya da yüksek göz içi basıncı (GİB) ile alakalı olduğu düşünülen, akut SRAT saptandı. Acil olarak, göz içinden silikon yağının bir kısmı çıkartıldı. Retinal ödem gerilemesine rağmen, hastanın görme keskinliğinde düzelme olmadı. Silikon yağının, doğrudan bası ve/veya yüksek GİB nedeniyle akut SRAT'na sebep olabileceği akılda tutulmalıdır. (Turk J Oph thal mol 2012; 42: 238-40) Anah tar Ke li me ler: Akut santral retinal arter tıkanıklığı, silikon yağı, pars plana vitrektomi, lensektomi

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Göz içi Silikon Yağı Tamponatı ile İlişkili Akut Santral Retinal Arter Tıkanıklığı

...

2012

Tjo

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“…49 Patients with gas in the globe should not have N 2 O. 50,51 Genotoxicity and teratogenicity An ex-vivo assessment of DNA damage in patients exposed to high concentrations of N 2 O during colorectal surgery showed increased genotoxicity compared with controls. 52 The clinical significance of the finding is unclear.…”

Section: Gastrointestinal Effectsmentioning

confidence: 99%

The adverse effects of nitrous oxide

Ferner

Mackenzie²,

Aronson³

2014

Adverse Drug Reaction Bulletin

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“…Central retinal artery occlusion has been reported in patients who have had general anaesthesia whilst having an intraocular gas bubble. There have been several reported cases of irreversible loss of vision from use of nitrous oxide during general anaesthesia (Hart, 2002, Kodjikian, 2003and Silvanus et al, 2008 In the acute case of elevated IOP, on the first post operative day, topical anti glaucoma medications (beta blockers, prostaglandin analogues, carbonic anhydrase inhibitors, alpha 2 agonists) and oral carbonic anhydrase inhibitors may be used. If the IOPs continue to increase, an anterior chamber paracentesis may be done or a small volume of gas may be aspirated from the vitreal cavity with a 27G needle and a 1ml syringe.…”

Section: Situations To Avoid In Patients With Intraocular Gas Situatimentioning

confidence: 99%

Secondary Glaucoma After Vitreoretinal Procedures

Mowatt¹

2011

Glaucoma - Current Clinical and Research Aspects

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Loss of vision caused by expansion of intraocular perfluoropropane (C3F8) gas during nitrous oxide anesthesia

Cited by 37 publications

References 7 publications

Göz içi Silikon Yağı Tamponatı ile İlişkili Akut Santral Retinal Arter Tıkanıklığı

Göz içi Silikon Yağı Tamponatı ile İlişkili Akut Santral Retinal Arter Tıkanıklığı

The adverse effects of nitrous oxide

Secondary Glaucoma After Vitreoretinal Procedures

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