Loss of Immunosuppressive Potency of Antilymphocyte Serum After Prolonged Storage

Evaluation of Rosette Inhibition Test in Renal Transplantation

“…Previous reports have suggested that there is a loss of the immunosuppressive potency of A.L.G. with storage (Judd and Trentin, 1971;Shanfield et al, 1971). Our unopened ampoules of A.L.G.…”

Analysis of 330 Necro-Kidney-Allografts (Part 2 of 2)

“…No influence on patient survival was observed (57, 103,104). Prospective studies will, however, have to decide about the real value of A L G treatment in allotransplantation.…”

Radiology and Organ Transplantation

“…Thus, the patient whose course is shown in Figure 1 required relatively massive doses of prednisone early in his convalescence, but steroid treatment was subsequently stopped without deterioration of homograft function. In animal laboratories, it has been shown (21, 25,27,[30][31][32]35) that all treatment may be discontinued in some recipients of whole-organ homografts with survival for many years. We have observed examples of this kind of "graft acceptance" after initial immunosuppressive treatment with 6-mercaptopurine, azathioprine, and heterologous antilymphocyte serum.…”