Loss of Hydroxyl Ions from Gutta-Percha Points with Calcium Hydroxide in Their Composition: An In Vivo Study

Azabal-Arroyo, Magdalena; Menasalvas-Ruiz, Gracia; Martín-Alonso, Javier; Arroquia, Juan José Hidalgo; Barrio, José María Vega-del

doi:10.1097/00004770-200210000-00005

Cited by 15 publications

(17 citation statements)

References 11 publications

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“…Azabal-Arroyo et al ., evaluated antimicrobial activity of materials containing Ca(OH) 2 in solid media presents some difficulties as there is low solubility of the Ca(OH) 2 in solid medium. [14] This fact could explain the results obtained in this study that show that the Gutta-percha points containing Ca(OH) 2 did not present antimicrobial activity on tested strains. Further long term studies need to be done to confirm the same.…”

Section: Discussionmentioning

confidence: 74%

In vitro evaluation of antimicrobial activity of different Gutta‑percha points and calcium hydroxide pastes

Jhamb

Chaurasia

Masamatti

et al. 2014

J Int Soc Prevent Communit Dent

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Purpose:To evaluate the antimicrobial activity of different compositions of Gutta-percha points and calcium hydroxide (Ca(OH)2) pastes, used in endodontic therapy.Materials and Methods:The evaluated material consisted of Gutta-percha points containing Ca(OH)2, Gutta-percha points containing chlorhexidine (Chx), conventional Gutta-percha points and Ca(OH)2 pastes. Antimicrobial properties of Chx and CaOH paste are compared with CaOH points. Antimicrobial tests included three species of microorganisms: Escherichia coli (ATCC 25923), Staphylococcus aureus (ATCC 25922) Pseudomonas aeruginosa (ATCC BAA-427), the agar disc diffusion method was employed. The plates were kept at room temperature for 2 h for prediffusion and then incubated at 37°C for 24 h. Zones of inhibition were measured.Results and Conclusion:All microbial species used in the study were inhibited by the Gutta-percha points containing Chx and by the Ca(OH)2 pastes, no antimicrobial activity was observed for the other groups (conventional Gutta-percha and Ca(OH)2 group).

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Section: Discussionmentioning

confidence: 74%

In vitro evaluation of antimicrobial activity of different Gutta‑percha points and calcium hydroxide pastes

Jhamb

Chaurasia

Masamatti

et al. 2014

J Int Soc Prevent Communit Dent

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“…[25] The calcium hydroxide containing gutta-percha points showed a significantly lower alkalizing potential than Ca (OH) 2 mixed with distilled water. Calt et al .…”

Section: Discussionmentioning

confidence: 99%

Evaluation of calcium ion release and change in pH on combining calcium hydroxide with different vehicles

Grover

Shetty

2014

Contemp Clin Dent

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Introduction:Intracanal medicaments have traditionally been used in endodontics to disinfect root canals between appointments. Calcium hydroxide is widely used as an intracanal medicament for disinfection and to promote periapical healing. It is stable for long periods, harmless to the body, and bactericidal in a limited area. The efficacy of calcium hydroxide as a disinfectant is dependent on the availability of the hydroxyl ions in the solution that depends on the vehicle in which the calcium hydroxide is carried. In general, three types of vehicles are used: Aqueous, viscous or oily. Some in vitro studies have shown that the type of vehicle has a direct relationship with the concentration and the velocity of ionic liberation as well as with the antibacterial action when the paste is carried into a contaminated area.Aim of the Study:To evaluate the calcium ion release and measure the change in pH of the environment that occurred when calcium hydroxide was combined with different vehicles (distilled water, propylene glycol, calcium hydroxide containing gutta-percha points and chitosan) over different time periods.Materials and Methods:Forty single rooted mandibular first premolar teeth were decoronated for this study. Working length was established and the root canals were enlarged and irrigation accomplished with 2 ml of NaOCl solution after every file. The teeth were then randomly divided into four groups. The canals were then packed with different preparations of calcium hydroxide using the following vehicles-distilled water, propylene glycol, gutta-percha points and chitosan. Calcium ion release in different groups was analyzed using an ultraviolet spectrophotometer at 220 nm. The change in pH of was determined using a pH meter. Results were statistically evaluated using one-way ANOVA test.Result:For calcium ion release, Group 2 showed cumulative drug release of 81.97% at the end of 15 days, whereas Group 1, 3 and 4 showed a release of 99.53, 17.98, 74.93% respectively with a significant difference among all groups. Group 1 reached the highest Ca2+ level (39.79%) at the end of 1 day but showed almost complete release of calcium hydroxide at the end of 15 days. Group 3 showed least calcium ion release (17.98%) at 15 days. Group 4 showed a sustained release of Ca+2 ions from 74% at 15 days to 95% at the end of 30 days. After the 1st h; Group 1 showed the highest pH level (11.8). However, pH reduced to 7.8 at the end of 30 days in this group. Group 2 showed the highest pH value (10.35), followed by Group 4 (10.32) after 30 days.Conclusion:Chitosan can be used as a promising vehicle for calcium hydroxide to maintain an alkaline pH and to allow sustained release of calcium ions in the root canal system.

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“…reported maximum pH values of 9.5 and 10.9, respectively. [21] Calt et al . showed that calcium hydroxide gutta-percha points did not induce any changes in pH and calcium ion levels.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of calcium ion, hydroxyl ion release and pH levels in various calcium hydroxide based intracanal medicaments: An in vitro study

et al. 2011

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Aims:Evaluation of calcium ion and hydroxyl ion release and pH levels in various calcium hydroxide based intracanal medicaments.Objective:The purpose of this study was to evaluate calcium and hydroxyl ion release and pH levels of calcium hydroxide based products, namely, RC Cal, Metapex, calcium hydroxide with distilled water, along with the new gutta-percha points with calcium hydroxide.Materials and Methods:The materials were inserted in polyethylene tubes and immersed in deionized water. The pH variation, Ca++ and OH- release were monitored periodically for 1 week. Statistical Analysis Used: Statistical analysis was carried out using one-way analysis of variance and Tukey's post hoc tests with PASW Statistics version 18 software to compare the statistical difference.Results:After 1 week, calcium hydroxide with distilled water and RC Cal raised the pH to 12.7 and 11.8, respectively, while a small change was observed for Metapex, calcium hydroxide gutta-percha points. The calcium released after 1 week was 15.36 mg/dL from RC Cal, followed by 13.04, 1.296, 3.064 mg/dL from calcium hydroxide with sterile water, Metapex and calcium hydroxide gutta-percha points, respectively.Conclusions:Calcium hydroxide with sterile water and RC Cal pastes liberate significantly more calcium and hydroxyl ions and raise the pH higher than Metapex and calcium hydroxidegutta-percha points.

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Loss of Hydroxyl Ions from Gutta-Percha Points with Calcium Hydroxide in Their Composition: An In Vivo Study

Cited by 15 publications

References 11 publications

In vitro evaluation of antimicrobial activity of different Gutta‑percha points and calcium hydroxide pastes

In vitro evaluation of antimicrobial activity of different Gutta‑percha points and calcium hydroxide pastes

Evaluation of calcium ion release and change in pH on combining calcium hydroxide with different vehicles

Evaluation of calcium ion, hydroxyl ion release and pH levels in various calcium hydroxide based intracanal medicaments: An in vitro study

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